Drug Information

Drug General Information
Drug ID
D03INQ
Former ID
DIB004185
Drug Name
Laevo-Bambuterol
Synonyms
R-Bambuterol; R-bambuterol hydrochloride
Indication Asthma [ICD10:J45] Phase 1 [549077]
Company
Dongguan Kaifa Biomedicine Inc
Canonical SMILES
CC(C)(NC[C@@H](c1cc(OC(=O)N(C)C)cc(OC(=O)N(C)C)c1)O)C.C<br />l
Target and Pathway
Target(s) Beta-3 adrenergic receptor Target Info Modulator [543746]
KEGG Pathway Calcium signaling pathway
cGMP-PKG signaling pathway
Neuroactive ligand-receptor interaction
Endocytosis
Salivary secretion
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Beta3 adrenergic receptor signaling pathway
Reactome Adrenoceptors
G alpha (s) signalling events
WikiPathways Monoamine GPCRs
Calcium Regulation in the Cardiac Cell
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 549077Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800031995)
Ref 543746(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 29).

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