Drug Information

Drug General Information
Drug ID
D03GAX
Former ID
DIB000037
Drug Name
TAK-802
Indication Urinary dysfunction [ICD10:N39.3-N39.4] Discontinued in Phase 2 [547886]
Company
Takeda Pharmaceutical Co Ltd
Canonical SMILES
N12c3c(cc(cc3CCC1=O)C(=O)CCC1CCN(Cc3cc(F)ccc3)CC1)CC2
Target and Pathway
Target(s) Acetylcholinesterase Target Info Inhibitor [526952]
KEGG Pathway Glycerophospholipid metabolism
Cholinergic synapse
PANTHER Pathway Muscarinic acetylcholine receptor 1 and 3 signaling pathway
Muscarinic acetylcholine receptor 2 and 4 signaling pathway
Nicotinic acetylcholine receptor signaling pathway
Pathway Interaction Database ATF-2 transcription factor network
PathWhiz Pathway Phospholipid Biosynthesis
WikiPathways Monoamine Transport
Biogenic Amine Synthesis
Acetylcholine Synthesis
Integrated Pancreatic Cancer Pathway
References
Ref 547886Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800020145)
Ref 526952Effects of TAK-802, a novel acetylcholinesterase inhibitor, on distension-induced rhythmic bladder contractions in rats and guinea pigs. Eur J Pharmacol. 2004 Feb 6;485(1-3):299-305.

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