Drug Information

Drug General Information
Drug ID
D03FZA
Former ID
DNC012073
Drug Name
FUSIDIENOL
Drug Type
Small molecular drug
Indication Discovery agent Terminated [545839]
Formula
C16H12O7
Canonical SMILES
COC(=O)C1=CC(=COC2=C1C(=O)C3=C(O2)C=CC=C3O)CO
InChI
1S/C16H12O7/c1-21-15(20)9-5-8(6-17)7-22-16-12(9)14(19)13-10(18)3-2-4-11(13)23-16/h2-5,7,17-18H,6H2,1H3
InChIKey
LJNGMSGIOXTZLN-UHFFFAOYSA-N
PubChem Compound ID
5492684
Target and Pathway
Target(s) Protein farnesyltransferase beta subunit Target Info Inhibitor [526296]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
References
Ref 545839Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800004994)
Ref 526296J Med Chem. 2002 Mar 28;45(7):1460-5.Modeling of binding modes and inhibition mechanism of some natural ligands of farnesyl transferase using molecular docking.

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