Drug Information

Drug General Information
Drug ID
D02QXF
Former ID
DNC005091
Drug Name
8-(1-Methyl-butoxy)-quinolin-2-ylamine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [527194]
Formula
C14H18N2O
Canonical SMILES
CCCC(C)OC1=CC=CC2=C1N=C(C=C2)N
InChI
1S/C14H18N2O/c1-3-5-10(2)17-12-7-4-6-11-8-9-13(15)16-14(11)12/h4,6-10H,3,5H2,1-2H3,(H2,15,16)
InChIKey
KMEFXXMANWGJCR-UHFFFAOYSA-N
PubChem Compound ID
11776033
Target and Pathway
Target(s) Melanin-concentrating hormone receptor 1 Target Info Inhibitor [527194]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
References
Ref 527194Bioorg Med Chem Lett. 2004 Oct 4;14(19):4873-7.Synthesis and evaluation of 2-amino-8-alkoxy quinolines as MCHr1 antagonists. Part 1.
Ref 527194Bioorg Med Chem Lett. 2004 Oct 4;14(19):4873-7.Synthesis and evaluation of 2-amino-8-alkoxy quinolines as MCHr1 antagonists. Part 1.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.