Drug Information

Drug General Information
Drug ID
D02JUM
Former ID
DIB015747
Drug Name
METIAPRIL
Synonyms
Methiopril; Cis-1-[3-(Acetylsulfanyl)propionyl]-6-methylpiperidine-2-carboxylic acid
Indication Hypotension [ICD9: 458, 796.3; ICD10:I95] Discontinued in Phase 2 [545860]
Target and Pathway
Target(s) Angiotensin-converting enzyme Target Info Inhibitor [534099]
KEGG Pathway Renin-angiotensin system
Chagas disease (American trypanosomiasis)
Hypertrophic cardiomyopathy (HCM)
PathWhiz Pathway Angiotensin Metabolism
Reactome Metabolism of Angiotensinogen to Angiotensins
WikiPathways ACE Inhibitor Pathway
Metabolism of Angiotensinogen to Angiotensins
References
Ref 545860Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005081)
Ref 534099The clinical efficacy of the first Russian angiotensin-converting enzyme inhibitor methiopril in patients with heart failure. Klin Med (Mosk). 1995;73(3):49-51.

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