Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D02JIN
|
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| Former ID |
DIB005192
|
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| Drug Name |
264W94
|
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| Synonyms |
GW-264
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| Drug Type |
Small molecular drug
|
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| Company |
Glaxo Wellcome plc
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| Formula |
C23H31NO4S
|
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| InChI |
InChI=1S/C23H31NO4S/c1-5-7-13-23(6-2)16-29(25,26)21-15-20(28-4)19(27-3)14-18(21)22(24-23)17-11-9-8-10-12-17/h8-12,14-15,22,24H,5-7,13,16H2,1-4H3/t22-,23-/m1/s1
|
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| InChIKey |
CKFWDLFFXXVSBJ-DHIUTWEWSA-N
|
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| CAS Number |
CAS 178961-24-5
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Ileal bile acid transfer | Target Info | Modulator | [531629] | |
| KEGG Pathway | Bile secretion | ||||
| Reactome | Recycling of bile acids and salts | ||||
| WikiPathways | Bile acid and bile salt metabolism | ||||
| References | |||||
| Ref 531629 | Inhibition of apical sodium-dependent bile acid transporter as a novel treatment for diabetes. Am J Physiol Endocrinol Metab. 2012 Jan 1;302(1):E68-76. | ||||
| Ref 541657 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6529). | ||||
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