Drug Information

Drug General Information
Drug ID
D02CLU
Former ID
DIB007342
Drug Name
DNA vaccine
Synonyms
DNA vaccine (melanoma); DNA vaccine (cancer), Memorial Sloan-Kettering Cancer Center; DNA vaccine (melanoma), Memorial Sloan-Kettering Cancer Center
Drug Type
Vaccine
Indication Melanoma [ICD9: 172; ICD10:C43] Phase 1 [529003]
Company
Memorial Sloan-Kettering Cancer Center
Target and Pathway
Target(s) Tyrosine oxidase Target Info [529003]
BioCyc Pathway (S)-reticuline biosynthesis
Eumelanin biosynthesis
L-dopachrome biosynthesis
KEGG Pathway Tyrosine metabolism
Riboflavin metabolism
Metabolic pathways
Melanogenesis
PathWhiz Pathway Riboflavin Metabolism
Tyrosine Metabolism
WikiPathways Dopamine metabolism
References
Ref 529003Safety and immunogenicity of tyrosinase DNA vaccines in patients with melanoma. Mol Ther. 2007 Nov;15(11):2044-50. Epub 2007 Aug 28.
Ref 529003Safety and immunogenicity of tyrosinase DNA vaccines in patients with melanoma. Mol Ther. 2007 Nov;15(11):2044-50. Epub 2007 Aug 28.

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