Drug Information

Drug General Information
Drug ID
D02BGR
Former ID
DIB018116
Drug Name
(S)-N-[1-(3-morpholin-4-yl-phenyl)-ethyl]-3-phenyl-acrylamide
Synonyms
(S)-1 [PMID: 16904708]; compound 2 [PMID: 12852750]
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528363]
Formula
C21H24N2O2
InChI
InChI=1S/C21H24N2O2/c1-17(22-21(24)11-10-18-6-3-2-4-7-18)19-8-5-9-20(16-19)23-12-14-25-15-13-23/h2-11,16-17H,12-15H2,1H3,(H,22,24)/b11-10+/t17-/m0/s1
InChIKey
QMIMHUDEVKGOTQ-DVQDXYAYSA-N
PubChem Compound ID
9949648
PubChem Substance ID
14924627, 15348173, 24220280, 79871357, 99355544, 103312883, 104021922, 135650748, 140281430, 143360201, 232329869
Target and Pathway
Target(s) Potassium voltage-gated channel subfamily KQT member 4 Target Info Activator [528363]
Kv7.5 Target Info Activator [528363]
Potassium voltage-gated channel subfamily KQT member 2 Target Info Activator [528363]
KEGG Pathway Cholinergic synapsehsa04725:Cholinergic synapse
PANTHER Pathway Muscarinic acetylcholine receptor 1 and 3 signaling pathway
Reactome Voltage gated Potassium channelsR-HSA-1296072:Voltage gated Potassium channels
Interaction between L1 and Ankyrins
WikiPathways Potassium ChannelsWP2669:Potassium Channels
L1CAM interactions
References
Ref 528363The acrylamide (S)-1 differentially affects Kv7 (KCNQ) potassium channels. Neuropharmacology. 2006 Nov;51(6):1068-77. Epub 2006 Aug 10.
Ref 528363The acrylamide (S)-1 differentially affects Kv7 (KCNQ) potassium channels. Neuropharmacology. 2006 Nov;51(6):1068-77. Epub 2006 Aug 10.

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