Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D02AYX
|
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| Former ID |
DNC010279
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| Drug Name |
2H-chromeno[2,3-d]pyrimidine-2,4(3H)-dione
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [530608] | ||
| Formula |
C11H6N2O3
|
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| Canonical SMILES |
C1=CC=C2C(=C1)C=C3C(=O)NC(=O)N=C3O2
|
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| InChI |
1S/C11H6N2O3/c14-9-7-5-6-3-1-2-4-8(6)16-10(7)13-11(15)12-9/h1-5H,(H,12,14,15)
|
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| InChIKey |
BFMCRAXOACCPEL-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | NAD-dependent deacetylase sirtuin-1 | Target Info | Inhibitor | [530608] | |
| PANTHER Pathway | p53 pathway | ||||
| Pathway Interaction Database | p73 transcription factor network | ||||
| Signaling events mediated by HDAC Class III | |||||
| E2F transcription factor network | |||||
| HIF-2-alpha transcription factor network | |||||
| Signaling events mediated by HDAC Class I | |||||
| FoxO family signaling | |||||
| Regulation of Androgen receptor activity | |||||
| Regulation of retinoblastoma protein | |||||
| References | |||||
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