Drug Information

Drug General Information
Drug ID
D01XGX
Former ID
DIB003724
Drug Name
JTP-4819
Synonyms
JTP-3399
Drug Type
Small molecular drug
Indication Cognitive disorders [ICD9: 290-294, 294.0, 780.09, 780.9, 780.93; ICD10:F01-F07, F04, F05, R41.3] Discontinued in Phase 2 [546065]
Company
Japan Tobacco Inc
Formula
C19H25N3O4
Canonical SMILES
N1(C(=O)[C@H]2N(C(=O)NCc3ccccc3)CCC2)[C@H](C(=O)CO)CCC1
CAS Number
CAS 162203-65-8
PubChem Compound ID
178060
Target and Pathway
Target(s) Prolyl endopeptidase Target Info Modulator [534339]
KEGG Pathway Renin-angiotensin system
PANTHER Pathway Vasopressin synthesis
References
Ref 546065Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006163)
Ref 534339A novel prolyl endopeptidase inhibitor, JTP-4819, with potential for treating Alzheimer's disease. Behav Brain Res. 1997 Feb;83(1-2):147-51.

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