Drug Information

Drug General Information
Drug ID
D01VNL
Former ID
DIB012441
Drug Name
JM-1232(-)
Synonyms
Sedative, Maruishi; Benzodiazepine agonist (sedation), Maruishi
Indication Anesthesia [ICD9: 338; ICD10:R20.0] Investigative [543814]
Company
Maruishi Pharmaceutical Co Ltd
Canonical SMILES
O=C1c2cc3c(cc2[C@H](N1c1ccccc1)CC(=O)N1CCN(CC1)C)CCC3
Target and Pathway
Target(s) GABA A receptor Target Info Agonist [543814]
KEGG Pathway Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
GABAergic synapse
Morphine addiction
Nicotine addiction
Reactome Ligand-gated ion channel transport
GABA A receptor activation
WikiPathways SIDS Susceptibility Pathways
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Iron uptake and transport
References
Ref 543814(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 415).
Ref 543814(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 415).

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