Drug Information

Drug General Information
Drug ID
D01UNC
Former ID
DNC013624
Drug Name
2-(4-aminophenylsulfonamido)acetic acid
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529308]
Formula
C8H10N2O4S
Canonical SMILES
C1=CC(=CC=C1N)S(=O)(=O)NCC(=O)O
InChI
1S/C8H10N2O4S/c9-6-1-3-7(4-2-6)15(13,14)10-5-8(11)12/h1-4,10H,5,9H2,(H,11,12)
InChIKey
BPJUMYMTQYMSFZ-UHFFFAOYSA-N
PubChem Compound ID
412201
Target and Pathway
Target(s) Aldose reductase Target Info Inhibitor [529308]
BioCyc Pathway Methylglyoxal degradation III
Acetone degradation I (to methylglyoxal)
KEGG Pathway Pentose and glucuronate interconversions
Fructose and mannose metabolism
Galactose metabolism
Glycerolipid metabolism
Metabolic pathways
NetPath Pathway IL1 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
PathWhiz Pathway Fructose and Mannose Degradation
Pyruvate Metabolism
Pterine Biosynthesis
Glycerolipid Metabolism
Galactose Metabolism
WikiPathways Metapathway biotransformation
Polyol Pathway
Metabolism of steroid hormones and vitamin D
References
Ref 529308Bioorg Med Chem. 2008 Apr 1;16(7):3926-32. Epub 2008 Jan 30.Design and synthesis of N-(3,5-difluoro-4-hydroxyphenyl)benzenesulfonamides as aldose reductase inhibitors.
Ref 529308Bioorg Med Chem. 2008 Apr 1;16(7):3926-32. Epub 2008 Jan 30.Design and synthesis of N-(3,5-difluoro-4-hydroxyphenyl)benzenesulfonamides as aldose reductase inhibitors.

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