Drug Information

Drug General Information
Drug ID
D00TVI
Former ID
DIB015118
Drug Name
SR-58894A
Indication Gastrointestinal disease [ICD10:K00-K93] Terminated [546455]
Company
Sanofi-Synthelabo
Canonical SMILES
c12[C@@H](NC[C@@H](COc3c(CC=C)cccc3)O)CCCc1cccc2.Cl
CAS Number
CAS 132017-03-9
Target and Pathway
Target(s) Beta-3 adrenergic receptor Target Info Modulator [527168]
KEGG Pathway Calcium signaling pathway
cGMP-PKG signaling pathway
Neuroactive ligand-receptor interaction
Endocytosis
Salivary secretion
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Beta3 adrenergic receptor signaling pathway
Reactome Adrenoceptors
G alpha (s) signalling events
WikiPathways Monoamine GPCRs
Calcium Regulation in the Cardiac Cell
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 546455Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800008218)
Ref 527168Pharmacological characterization of beta-adrenoceptor subtypes mediating relaxation in porcine isolated ureteral smooth muscle. J Urol. 2004 Sep;172(3):1155-9.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.