Drug Information

Drug General Information
Drug ID
D00HLW
Former ID
DIB021225
Drug Name
WZ4003
Synonyms
WZ-4003
Drug Type
Small molecular drug
Indication Discovery agent Investigative [532526]
Formula
C25H29ClN6O3
InChI
InChI=1S/C25H29ClN6O3/c1-4-23(33)28-17-6-5-7-19(14-17)35-24-20(26)16-27-25(30-24)29-21-9-8-18(15-22(21)34-3)32-12-10-31(2)11-13-32/h5-9,14-16H,4,10-13H2,1-3H3,(H,28,33)(H,27,29,30)
InChIKey
SDGJBAUIGHSMRI-UHFFFAOYSA-N
PubChem Compound ID
72200024
PubChem Substance ID
174009344, 210275365, 210281013, 226088080, 249565727, 249896034, 251910626, 252110337, 252158660, 252160972, 252216615, 252473900
Target and Pathway
Target(s) NUAK family, SNF1-like kinase, 2 Target Info Inhibitor [532526]
NUAK family, SNF1-like kinase, 1 Target Info Inhibitor [532526]
References
Ref 532526Characterization of WZ4003 and HTH-01-015 as selective inhibitors of the LKB1-tumour-suppressor-activated NUAK kinases. Biochem J. 2014 Jan 1;457(1):215-25.
Ref 532526Characterization of WZ4003 and HTH-01-015 as selective inhibitors of the LKB1-tumour-suppressor-activated NUAK kinases. Biochem J. 2014 Jan 1;457(1):215-25.

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