Drug Information

Drug General Information
Drug ID
D00CQT
Former ID
DNC000554
Drug Name
Dichloroallyl lawsone
Drug Type
Small molecular drug
Indication Discovery agent Investigative [535540]
Formula
C13H8Cl2O3
Canonical SMILES
C1=CC=C2C(=C1)C(=C(C(=O)C2=O)CC=C(Cl)Cl)O
InChI
1S/C13H8Cl2O3/c14-10(15)6-5-9-11(16)7-3-1-2-4-8(7)12(17)13(9)18/h1-4,6,16H,5H2
InChIKey
LWQZLQISFLBSGW-UHFFFAOYSA-N
CAS Number
CAS 36417-16-0
PubChem Compound ID
277767
PubChem Substance ID
418677, 604240, 5189097, 11405011, 11446690, 14848815, 41297817, 42683017, 49995610, 56189109, 57401015, 79615181, 92764015, 103123311, 104448858, 117452463, 124633051, 134339953, 134999031, 137270193, 138857227, 142558192, 162844755, 237236815, 241065687, 242421272, 250099657
Target and Pathway
Target(s) Dihydroorotate dehydrogenase, mitochondrial Target Info Inhibitor [535540]
KEGG Pathway Pyrimidine metabolism
Metabolic pathways
PathWhiz Pathway Pyrimidine Metabolism
Reactome Pyrimidine biosynthesis
WikiPathways Metabolism of nucleotides
References
Ref 535540Malarial dihydroorotate dehydrogenase. Substrate and inhibitor specificity. J Biol Chem. 2002 Nov 1;277(44):41827-34. Epub 2002 Aug 19.
Ref 535540Malarial dihydroorotate dehydrogenase. Substrate and inhibitor specificity. J Biol Chem. 2002 Nov 1;277(44):41827-34. Epub 2002 Aug 19.

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