Drug Information

Drug General Information
Drug ID
D00BAJ
Former ID
DIB020134
Drug Name
KH-CB19
Synonyms
KH CB19
Drug Type
Small molecular drug
Indication Discovery agent Investigative [531319]
Formula
C15H13Cl2N3O2
InChI
InChI=1S/C15H13Cl2N3O2/c1-3-22-15(21)14-11(8(6-18)7-19)9-4-5-10(16)12(17)13(9)20(14)2/h4-6H,3,18H2,1-2H3/b8-6-
InChIKey
CXJCGSPAPOTTSF-VURMDHGXSA-N
PubChem Compound ID
44237094
PubChem Substance ID
85256594, 99445162, 104252755, 125258868, 137185070, 162103431, 170474610, 170481537, 172131337, 241376896, 249565735, 249618126, 252479278
Target and Pathway
Target(s) CDC-like kinase 3 Target Info Inhibitor [531348]
Cdc2-like kinase 1 Target Info Inhibitor [531348]
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A Target Info Inhibitor [531348]
NetPath Pathway TCR Signaling Pathway
EGFR1 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
WikiPathways mRNA Processing
References
Ref 531319Liver X receptors as regulators of macrophage inflammatory and metabolic pathways. Biochim Biophys Acta. 2011 Aug;1812(8):982-94.
Ref 531348Specific CLK inhibitors from a novel chemotype for regulation of alternative splicing. Chem Biol. 2011 Jan 28;18(1):67-76.

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