Details of Protein (Pro) | MIAOME

General Information of Protein (ID: PT018)
Protein Name		Lethal toxin
Unify Protein name		Lethal factor
Protein Synonym		Anthrax lethal toxin endopeptidase component
Protein Entry		P15917
Protein Entry name		LEF_BACAN
Protein Length		809AA
Gene name		lef
Gene synonym		pXO1-107, BXA0172, GBAA_pXO1_0172
Gene ID		45025515
Gene Location		Plasmid pXO1: 149,357-151,786

The epigenetic modification information of this protein
Modification Type																				Molecule																				EM Info								Cell/Tissue Type																		Modified sites																						Condition															REF
Histone Acetylation																				H3																				EM Info								Epithelial cells																		lysine 14																						.															[1]
Histone Phosphorylation																				H3																				EM Info								Epithelial cells																		serine 10																						.															[1]

The microbes that produce this protein
Microbiota Name: Bacillus anthracis
Detailed Information		MIC Info click to show the detail information of this Microbiota					[1]
Description		Bacillus anthracis is a gram-positive and rod-shaped bacteria that causes anthrax, a deadly disease to livestock and, occasionally, to humans. It is the only permanent pathogen within the genus Bacillus.

References
1	Anthrax lethal toxin impairs IL-8 expression in epithelial cells through inhibition of histone H3 modification PLoS Pathog. 2009 Apr;5(4):e1000359. doi: 10.1371/journal.ppat.1000359. Epub 2009 Apr 3.

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