| General Information of MIC (ID: MC1069) |
| MIC Name |
Ehrlichia chaffeensis
|
| Lineage |
Kingdom: Bacteria
Phylum: Proteobacteria
Class: Alphaproteobacteria
Order: Rickettsiales
Family: Anaplasmataceae
Genus: Ehrlichia
|
| Gram |
Negative
|
| Host Relationship |
Pathogen
|
| Genome Size (bp) |
1176248
|
| Description |
Ehrlichia chaffeensis is an obligate intracellular, gram-negative species of Rickettsiales bacteria. It is a zoonotic pathogen transmitted to humans by the lone star tick. It is the causative agent of human monocytic ehrlichiosis.
|
| External Links |
Taxonomy ID |
945
|
| GOLD Database ID |
Go0033515
|
| GIMICA ID |
MIC00523
|
| Full List of Protein(s) Produced by This MIC |
| Protein Type: Microbial secreted proteins |
|---|
| Protein Name: TRP120 |
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|
| Detailed Infomation |
Pro Info
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|
| Modification Type |
Molecule |
EM Info |
Cell/Tissue Type |
Modified sites |
Condition |
REF |
| Histone Ubiquitination |
H2A |
EM Info
|
THP-1 cells |
lysine 119 |
Ehrlichia chaffeensis infection |
[1]
|
| Protein Name: TRP32 |
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|
| Detailed Infomation |
Pro Info
click to show the detail information of this protein
|
| Modification Type |
Molecule |
EM Info |
Cell/Tissue Type |
Modified sites |
Condition |
REF |
| Histone Deacetylation |
HDAC |
EM Info
|
. |
. |
. |
[2]
|
| Histone Methylation |
Histone Methylases |
EM Info
|
. |
. |
. |
[2]
|
| References |
| 1 |
Ehrlichia chaffeensis TRP120 Effector Targets and Recruits Host Polycomb Group Proteins for Degradation To Promote Intracellular Infection. Infect Immun. 2018 Mar 22;86(4):e00845-17. doi: 10.1128/IAI.00845-17. Print 2018 Apr.
|
| 2 |
Bacterial Factors Targeting the Nucleus: The Growing Family of Nucleomodulins Toxins (Basel). 2020 Mar 31;12(4):220. doi: 10.3390/toxins12040220.
|
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