Details of Epigenetic Molecule(EM)

General Information of EM (ID: EM12307)
Official Symbol		PCOTH
Official Full Name		Prostate And Testis Expressed Opposite C1QTNF9B And MIPEP
Synonym		Prostate And Testis Expressed Opposite C1QTNF9B And MIPEP;Pro-X-Gly Collagen Triple Helix Like Repeat Containing;C1QTNF9B Antisense RNA 1;C1QTNF9B-AS1;C1QTNF9B Antisense RNA 1 (Non-Protein Coding);HSALNG0095755
Molecule Type		Protein coding
Position On Chromosome		chr13(Start:23888842 - End:23909249)
Strand		+
Uniprot Entry		Q58A44
ENSG ID		ENSG00000205861

Metabolite(s) with this epigenetic modification
Metabolite Name: Valerate
Detailed Information	Meta Info click to show the detail information of this Metabolite	[1], [2]
Description	Valerate has been shown to hypermethylate PCOTH CpG site in breast cancer cells.

References
1	Valerian and valeric acid inhibit growth of breast cancer cells possibly by mediating epigenetic modifications. Sci Rep. 2021 Jan 28;11(1):2519. doi: 10.1038/s41598-021-81620-x.
2	Gut Microbiota as Important Mediator Between Diet and DNA Methylation and Histone Modifications in the Host. Nutrients. 2020 Feb 25;12(3):597. doi: 10.3390/nu12030597.

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