Details of Epigenetic Molecule(EM)

General Information of EM (ID: EM12232)
  Official Symbol
MRPS7
  Official Full Name
Mitochondrial Ribosomal Protein S7
  Synonym
Mitochondrial Ribosomal Protein S7;MRP-S;RP-S7;RPMS7;Mitochondrial Small Ribosomal Subunit Protein US7m;28S Ribosomal Protein S7, Mitochondrial;30S Ribosomal Protein S7 Homolog;COXPD34;MRP-S7;BMRP27a;BMRP-27a
  Molecule Type
Protein coding
  Position On Chromosome
chr17(Start:75261674 - End:75266376)
  Strand
+
  Uniprot Entry
Q9Y2R9 
  ENSG ID
ENSG00000125445 
    Disease Relevance (Click to Show/Hide)
         2C30: Melanoma of skin Cutaneous Melanoma [Melanoma of skin]
            Detailed Information Disease Link click to show the detail information of this Disease
         5A02: Thyrotoxicosis Graves' disease [Thyrotoxicosis]
            Detailed Information Disease Link click to show the detail information of this Disease
Metabolite(s) with this epigenetic modification
  Metabolite Name: Valerate
     Detailed Information Meta Info click to show the detail information of this Metabolite [1], [2]
     Description
Valerate has been shown to hypermethylate MRPS7 CpG site in breast cancer cells.

References
1 Valerian and valeric acid inhibit growth of breast cancer cells possibly by mediating epigenetic modifications. Sci Rep. 2021 Jan 28;11(1):2519. doi: 10.1038/s41598-021-81620-x.
2 Gut Microbiota as Important Mediator Between Diet and DNA Methylation and Histone Modifications in the Host. Nutrients. 2020 Feb 25;12(3):597. doi: 10.3390/nu12030597.

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