Details of Epigenetic Molecule(EM)

General Information of EM (ID: EM12119)
Official Symbol		H2BC15
Official Full Name		H2B Clustered Histone 15
Synonym		H2B Clustered Histone 15;H2B/D;HIST1H2BN;Histone Cluster 1 H2B Family Member N;H2BFD;Histone H2B.D
Molecule Type		Protein coding
Position On Chromosome		chr6(Start:27838545 - End:27855709)
Strand		+
Uniprot Entry		Q99877
ENSG ID		ENSG00000233822

Metabolite(s) with this epigenetic modification
Metabolite Name: Valerate
Detailed Information	Meta Info click to show the detail information of this Metabolite	[1], [2]
Description	Valerate has been shown to hypermethylate HIST1H2BN CpG site in breast cancer cells.

References
1	Valerian and valeric acid inhibit growth of breast cancer cells possibly by mediating epigenetic modifications. Sci Rep. 2021 Jan 28;11(1):2519. doi: 10.1038/s41598-021-81620-x.
2	Gut Microbiota as Important Mediator Between Diet and DNA Methylation and Histone Modifications in the Host. Nutrients. 2020 Feb 25;12(3):597. doi: 10.3390/nu12030597.

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