Details of Epigenetic Molecule(EM)

General Information of EM (ID: EM12039)
Official Symbol		EIF4EBP3
Official Full Name		Eukaryotic Translation Initiation Factor 4E Binding Protein 3
Synonym		Eukaryotic Translation Initiation Factor 4E Binding Protein 3;4E-BP3;Eukaryotic Translation Initiation Factor 4E-Binding Protein 3;EIF4E-Binding Protein 3;Eukaryotic Initiation Factor 4E-Binding Protein 3;4EBP3
Molecule Type		Protein coding
Position On Chromosome		chr5(Start:140547662 - End:140549576)
Strand		+
Uniprot Entry		O60516
ENSG ID		ENSG00000243056

Metabolite(s) with this epigenetic modification
Metabolite Name: Valerate
Detailed Information	Meta Info click to show the detail information of this Metabolite	[1], [2]
Description	Valerate has been shown to hypomethylateEIF4EBP3 CpG site in breast cancer cells.

References
1	Valerian and valeric acid inhibit growth of breast cancer cells possibly by mediating epigenetic modifications. Sci Rep. 2021 Jan 28;11(1):2519. doi: 10.1038/s41598-021-81620-x.
2	Gut Microbiota as Important Mediator Between Diet and DNA Methylation and Histone Modifications in the Host. Nutrients. 2020 Feb 25;12(3):597. doi: 10.3390/nu12030597.

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