Details of Epigenetic Molecule(EM)
| General Information of EM (ID: EM11902) | |||||||
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| Official Symbol |
BRD2
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| Official Full Name |
Bromodomain Containing 2
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| Synonym |
Bromodomain Containing 2;RING3;Bromodomain Containing 2;D6S113E;FSRG1;NAT;Really Interesting New Gene 3 Protein
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| Molecule Type |
Protein coding
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| Position On Chromosome |
chr6(Start:32968594 - End:32981505)
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| Strand |
+
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| Uniprot Entry | |||||||
| ENSG ID | |||||||
| Disease Relevance (Click to Show/Hide) | |||||||
| 2C30: Melanoma of skin | Cutaneous Melanoma [Melanoma of skin] | ||||||
| Detailed Information |
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| 5A02: Thyrotoxicosis | Graves' disease [Thyrotoxicosis] | ||||||
| Detailed Information |
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| 6B01: Panic disorder | Panic Disorder [Panic disorder] | ||||||
| Detailed Information |
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| 8A00: Parkinsonism | Parkinson's disease (PD) [Parkinsonism] | ||||||
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| 8A01: Choreiform disorders | Huntington's disease (HD) [Choreiform disorders] | ||||||
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| 8A20: Alzheimer disease | Alzheimer's disease [Alzheimer disease] | ||||||
| Detailed Information |
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| 9B75: Macular disorders | Age-related macular degeneration (AMD) [Macular disorders] | ||||||
| Detailed Information |
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| CB03: Idiopathic interstitial pneumonitis | Idiopathic pulmonary fibrosis (IPF) [Idiopathic interstitial pneumonitis] | ||||||
| Detailed Information |
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| DD70: Crohn disease | Crohn's disease [Crohn disease] | ||||||
| Detailed Information |
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| LD2C: Overgrowth syndromes | Sotos syndrome(SS) [Overgrowth syndromes] | ||||||
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| SE30: Developmental delay disorder | CHARGE and Kabuki syndromes [Developmental delay disorder] | ||||||
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| XH4KA9: Burkitt lymphoma | Burkitt Lymphoma [Burkitt lymphoma] | ||||||
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| XH4XG8: Chronic myeloid leukaemia | Chronic Phase-Chronic Myeloid Leukemia [Chronic myeloid leukaemia] | ||||||
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| XH5QN3: Nephroblastoma | Wilms tumor [Nephroblastoma] | ||||||
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| XN3DY: Helicobacter pylori | Helicobacter pylori infection [Helicobacter pylori] | ||||||
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| ZERO(Not Found): Glomerular diseases | IgA nephropathy [Glomerular diseases] | ||||||
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| Metabolite(s) with this epigenetic modification | |||||||
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| Metabolite Name: Valerate | |||||||
| Detailed Information |
Meta Info
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[1], [2] | |||||
| Description |
Valerate has been shown to hypermethylate BRD2 CpG site in breast cancer cells.
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