Details of Epigenetic Molecule(EM)

General Information of EM (ID: EM11823)
Official Symbol		ZNF488
Official Full Name		zinc finger protein 488
Synonym		FLJ32104
Molecule Type		Protein coding
Position On Chromosome		chr10(Start:47365496 - End:47384293)
Strand		-
Uniprot Entry		Q96MN9
ENSG ID		ENSG00000265763
Dnmivd Disease		BLCA

Metabolite(s) with this epigenetic modification
Metabolite Name: Valerate
Detailed Information	Meta Info click to show the detail information of this Metabolite	[1], [2]
Description	Valerate has been shown to hypermethylate ZNF488 CpG site in breast cancer cells.

References
1	Gut Microbiota as Important Mediator Between Diet and DNA Methylation and Histone Modifications in the Host. Nutrients. 2020 Feb 25;12(3):597. doi: 10.3390/nu12030597.
2	Heterochromatinization induced by GAA-repeat hyperexpansion in Friedreich's ataxia can be reduced upon HDAC inhibition by vitamin B3. Hum Mol Genet. 2013 Jul 1;22(13):2662-75. doi: 10.1093/hmg/ddt115. Epub 2013 Mar 7.

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