Details of Epigenetic Molecule(EM)

General Information of EM (ID: EM11232)
Official Symbol		MPRIP
Official Full Name		myosin phosphatase Rho interacting protein
Synonym		M-RIP;p116Rip;RHOIP3
Molecule Type		Protein coding
Position On Chromosome		chr17(Start:17042457 - End:17217679)
Strand		+
Uniprot Entry		Q6WCQ1
ENSG ID		ENSG00000133030
Dnmivd Disease		BLCA

Metabolite(s) with this epigenetic modification
Metabolite Name: Valerate
Detailed Information	Meta Info click to show the detail information of this Metabolite	[1], [2]
Description	Valerate has been shown to hypermethylate MPRIP CpG site in breast cancer cells.

References
1	Gut Microbiota as Important Mediator Between Diet and DNA Methylation and Histone Modifications in the Host. Nutrients. 2020 Feb 25;12(3):597. doi: 10.3390/nu12030597.
2	Arachidonic and oleic acid exert distinct effects on the DNA methylome. Epigenetics. 2016 May 3;11(5):321-34. doi: 10.1080/15592294.2016.1161873. Epub 2016 Apr 18.

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