Details of Epigenetic Molecule(EM)

General Information of EM (ID: EM10754)
  Official Symbol
MIR22
  Official Full Name
microRNA 22
  Synonym
hsa-mir-22;MIRN22
  Molecule Type
miRNA
  Position On Chromosome
chr17(Start:1713903 - End:1713987)
  Strand
-
  ENSG ID
ENSG00000283824 
  Dnmivd Disease
BLCA 
Metabolite(s) with this epigenetic modification
  Metabolite Name: Folate (B9)
     Detailed Information Meta Info click to show the detail information of this Metabolite [1], [2]
     Description
Folate has been shown to upregulate the expression of miR-22-3p in HL-7702 cells.
  Metabolite Name: Folate (B9)
     Detailed Information Meta Info click to show the detail information of this Metabolite [3], [1]
     Description
Folate has been shown to upregulate the expression of miR-22-3p in QGY-7703 cells.
  Metabolite Name: Folate (B9)
     Detailed Information Meta Info click to show the detail information of this Metabolite [4], [5]
     Description
Folate has been shown to upregulate the expression of miR-22-3p in QGY-7703 cells.

References
1 Gut Microbiota as Important Mediator Between Diet and DNA Methylation and Histone Modifications in the Host. Nutrients. 2020 Feb 25;12(3):597. doi: 10.3390/nu12030597.
2 Arachidonic and oleic acid exert distinct effects on the DNA methylome. Epigenetics. 2016 May 3;11(5):321-34. doi: 10.1080/15592294.2016.1161873. Epub 2016 Apr 18.
3 Response of MiRNA-22-3p and MiRNA-149-5p to Folate Deficiency and the Differential Regulation of MTHFR Expression in Normal and Cancerous Human Hepatocytes. PLoS One. 2017 Jan 3;12(1):e0168049. doi: 10.1371/journal.pone.0168049. eCollection 2017.
4 Associations of dietary methyl donor intake with MLH1 promoter hypermethylation and related molecular phenotypes in sporadic colorectal cancer. Carcinogenesis. 2008 Sep;29(9):1765-73. doi: 10.1093/carcin/bgn074. Epub 2008 Mar 13.
5 Biosynthesis of Vitamins by Probiotic Bacteria.

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