Details of Epigenetic Molecule(EM)
| General Information of EM (ID: EM01181) | |||||||
|---|---|---|---|---|---|---|---|
| Official Symbol |
SLC30A6
|
||||||
| Official Full Name |
solute carrier family 30 member 6
|
||||||
| Synonym |
FLJ31101;ZNT6
|
||||||
| Molecule Type |
Protein coding
|
||||||
| Position On Chromosome |
chr2(Start:32165841 - End:32224379)
|
||||||
| Strand |
+
|
||||||
| Uniprot Entry | |||||||
| ENSG ID | |||||||
| Dnmivd Disease | |||||||
| Disease Relevance (Click to Show/Hide) | |||||||
| 1C62: Human immunodeficiency virus disease without mention of tuberculosis or malaria | Acquired immune deficiency syndrome [Human immunodeficiency virus disease without mention of tuberculosis or malaria] | ||||||
| Detailed Information |
Disease Link
 click to show the detail information of this Disease
|
||||||
| 1F84: Opisthorchiasis | Opisthorchis viverrini [Opisthorchiasis] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 2A00: Primary neoplasms of brain | Glioma [Primary neoplasms of brain] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 2A01: Primary neoplasms of meninges | Meningioma [Primary neoplasms of meninges] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 2A90: Mature T-cell lymphoma, specified types, nodal or systemic | Anaplastic large cell lymphoma (ALCL) [Mature T-cell lymphoma, specified types, nodal or systemic] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 2B6B: Malignant neoplasms of nasopharynx | Nasopharyngeal carcinoma (NPC) [Malignant neoplasms of nasopharynx] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 2B70: Malignant neoplasms of oesophagus | Barrett's esophagus and esophageal adenocarcinoma [Malignant neoplasms of oesophagus] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 2B70: Malignant neoplasms of oesophagus | Esophageal adenocarcinoma (EAC) [Malignant neoplasms of oesophagus] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 2B72: Malignant neoplasms of stomach | Gastric cancer [Malignant neoplasms of stomach] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 2B90: Malignant neoplasms of colon | Colorectal cancer [Malignant neoplasms of colon] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 2C10: Malignant neoplasm of pancreas | Pancreatic ductal adenocarcinoma (PDAC) [Malignant neoplasm of pancreas] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 2C25: Malignant neoplasms of bronchus or lung | Lung cancer [Malignant neoplasms of bronchus or lung] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 2C25: Malignant neoplasms of bronchus or lung | Lung adenocarcinoma [Malignant neoplasms of bronchus or lung] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 2C60: Carcinoma of breast | Breast cancer [Carcinoma of breast] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 2C82: Malignant neoplasms of prostate | Prostate cancer [Malignant neoplasms of prostate] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 2D10: Malignant neoplasms of thyroid gland | Thyroid tumors [Malignant neoplasms of thyroid gland] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 4A40: Lupus erythematosus | Systemic lupus erythematosus (SLE) [Lupus erythematosus] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 4A80: Allergic or hypersensitivity disorders involving the respiratory tract | Respiratory allergy [Allergic or hypersensitivity disorders involving the respiratory tract] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 5B81: Obesity | Obesity [Obesity] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 6A00: Disorders of intellectual development | Intellectual disability and congenital anomalies(ID/CA) [Disorders of intellectual development] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 6A02: Autism spectrum disorder | Autism [Autism spectrum disorder] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 6A20: Schizophrenia | Schizophrenia [Schizophrenia] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 6B01: Panic disorder | Panic Disorder [Panic disorder] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 6E8Z: Mental, behavioural or neurodevelopmental disorders | Psychiatric disorders [Mental, behavioural or neurodevelopmental disorders] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 8A20: Alzheimer disease | Alzheimer's disease [Alzheimer disease] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 8A40: Multiple sclerosis | Multiple sclerosis [Multiple sclerosis] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 9A01: Infectious disorders of eyelid | Human eye and its diseases [Infectious disorders of eyelid] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| BD40: Atherosclerotic chronic arterial occlusive disease | Atherosclerosis [Atherosclerotic chronic arterial occlusive disease] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| CA22: Chronic obstructive pulmonary disease | Chronic obstructive pulmonary disease (COPD) [Chronic obstructive pulmonary disease] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| CA23: Asthma | Asthma [Asthma] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| CB03: Idiopathic interstitial pneumonitis | Idiopathic pulmonary fibrosis (IPF) [Idiopathic interstitial pneumonitis] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| DA0C: Periodontal disease | Periodontitis [Periodontal disease] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| FA20: Rheumatoid arthritis | Rheumatoid arthritis [Rheumatoid arthritis] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| FA21: Psoriatic arthritis | Psoriatic [Psoriatic arthritis] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| GA10: Endometriosis | Endometriosis [Endometriosis] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| JA24: Pre-eclampsia | Preeclampsia (PE) [Pre-eclampsia] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| KA21: Disorders of newborn related to short gestation or low birth weight | Preterm birth [Disorders of newborn related to short gestation or low birth weight] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| LA4Z: Clefts of lip, alveolus or palate | Non-syndromic cleft lip and palate [Clefts of lip, alveolus or palate] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| SD86: Dementia disorder | Dementia [Dementia disorder] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| SE30: Developmental delay disorder | CHARGE and Kabuki syndromes [Developmental delay disorder] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| XB8M: Congenital | Melanoma [Congenital] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| XH1E13: Germinoma | Germinoma [Germinoma] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| XH1ND9: Papillary carcinoma of thyroid | Papillary thyroid carcinoma [Papillary carcinoma of thyroid] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| XH1XF3: Osteosarcoma | Osteosarcoma [Osteosarcoma] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| XH3DV3: Adenoma | Adenoma [Adenoma] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| XH4546: Signet ring cell carcinoma | Signet ring cell colorectal cancer [Signet ring cell carcinoma] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| XH4S92: Leukaemia | Leukemia [Leukaemia] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| XH4W48: Hepatocellular carcinoma | Hepatocellular carcinoma (HCC) [Hepatocellular carcinoma] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| XH7F82: Glioblastoma | Glioblastoma [Glioblastoma] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| XH8AA5: Acute myeloid leukaemia | Acute myeloid leukemia (AML) [Acute myeloid leukaemia] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| XH8D74: Carcinomatosis | Cancer [Carcinomatosis] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| XH8P29: Medulloblastoma | Medulloblastoma [Medulloblastoma] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| XH8SH6: CNS embryonal tumour | Primitive neuroectodermal tumors [CNS embryonal tumour] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| XH9HQ1: Gastrointestinal stromal tumour | Gastrointestinal stromal tumors (GIST) [Gastrointestinal stromal tumour] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| Metabolite(s) with this epigenetic modification | |||||||
|---|---|---|---|---|---|---|---|
| Metabolite Name: Valerate | |||||||
| Detailed Information |
Meta Info
click to show the detail information of this Metabolite
|
[1], [2] | |||||
| Description |
Valerate has been shown to hypermethylate SLC30A6 CpG site in breast cancer cells.
|
||||||
| Protein(s) with this epigenetic modification | |||||||
|---|---|---|---|---|---|---|---|
| Protein Name: Rv2966c | |||||||
| Detailed Information |
Pro Info
click to show the detail information of this protein
|
[3] | |||||
| Description |
Rv2966c could hypermethylate the non-CpG dinucleotides at the host SLC30A6 (geneBody) genetic loci during Mycobacterium tuberculosis H37Rv infection.
|
||||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.