Details of Epigenetic Molecule(EM)

General Information of EM (ID: EM12506)
Official Symbol		ZKSCAN3
Official Full Name		Zinc Finger With KRAB And SCAN Domains 3
Synonym		Zinc Finger With KRAB And SCAN Domains 3;Zinc Finger Protein 306;Zinc Finger Protein 309;ZSCAN35;ZNF306;ZNF309;Zfp47;Zinc Finger And SCAN Domain-Containing Protein 13;ZF47;Zinc Finger Protein Zfp47;DJ874C20.1;ZFP306
Molecule Type		Protein coding
Position On Chromosome		chr6(Start:28349913 - End:28369174)
Strand		+
Uniprot Entry		Q9BRR0
ENSG ID		ENSG00000189298
Disease Relevance (Click to Show/Hide)
8A20: Alzheimer disease		Alzheimer's disease [Alzheimer disease]
Detailed Information		Disease Link click to show the detail information of this Disease

Metabolite(s) with this epigenetic modification
Metabolite Name: Valerate
Detailed Information	Meta Info click to show the detail information of this Metabolite	[1], [2]
Description	Valerate has been shown to hypermethylate ZKSCAN3 CpG site in breast cancer cells.

References
1	Valerian and valeric acid inhibit growth of breast cancer cells possibly by mediating epigenetic modifications. Sci Rep. 2021 Jan 28;11(1):2519. doi: 10.1038/s41598-021-81620-x.
2	Gut Microbiota as Important Mediator Between Diet and DNA Methylation and Histone Modifications in the Host. Nutrients. 2020 Feb 25;12(3):597. doi: 10.3390/nu12030597.

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