Details of Epigenetic Molecule(EM)

General Information of EM (ID: EM12440)
Official Symbol		TIMM8B
Official Full Name		Translocase Of Inner Mitochondrial Membrane 8 Homolog B
Synonym		Translocase Of Inner Mitochondrial Membrane 8 Homolog B;TIM8B;DDP2;Mitochondrial Import Inner Membrane Translocase Subunit Tim8 B;Deafness Dystonia Protein 2;FLJ21744;Translocase Of Inner Mitochondrial Membrane 8 Homolog B (Yeast);DDPL
Molecule Type		Protein coding
Position On Chromosome		chr11(Start:112084800 - End:112086798)
Strand		-
Uniprot Entry		Q9Y5J9
ENSG ID		ENSG00000150779

Metabolite(s) with this epigenetic modification
Metabolite Name: Valerate
Detailed Information	Meta Info click to show the detail information of this Metabolite	[1], [2]
Description	Valerate has been shown to hypermethylate TIMM8B CpG site in breast cancer cells.

References
1	Valerian and valeric acid inhibit growth of breast cancer cells possibly by mediating epigenetic modifications. Sci Rep. 2021 Jan 28;11(1):2519. doi: 10.1038/s41598-021-81620-x.
2	Gut Microbiota as Important Mediator Between Diet and DNA Methylation and Histone Modifications in the Host. Nutrients. 2020 Feb 25;12(3):597. doi: 10.3390/nu12030597.

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