Details of Epigenetic Molecule(EM)

General Information of EM (ID: EM12313)
Official Symbol		PFDN6
Official Full Name		Prefoldin Subunit 6
Synonym		Prefoldin Subunit 6;H2-KE2;KE-2;PFD6;KE2 Protein;Protein Ke2;HLA Class II Region Expressed Gene KE2
Molecule Type		Protein coding
Position On Chromosome		chr6(Start:33289302 - End:33298401)
Strand		+
Uniprot Entry		O15212
ENSG ID		ENSG00000204220

Metabolite(s) with this epigenetic modification
Metabolite Name: Valerate
Detailed Information	Meta Info click to show the detail information of this Metabolite	[1], [2]
Description	Valerate has been shown to hypermethylate PFDN6 CpG site in breast cancer cells.

References
1	Valerian and valeric acid inhibit growth of breast cancer cells possibly by mediating epigenetic modifications. Sci Rep. 2021 Jan 28;11(1):2519. doi: 10.1038/s41598-021-81620-x.
2	Gut Microbiota as Important Mediator Between Diet and DNA Methylation and Histone Modifications in the Host. Nutrients. 2020 Feb 25;12(3):597. doi: 10.3390/nu12030597.

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