Details of Epigenetic Molecule(EM)

General Information of EM (ID: EM12275)
Official Symbol		NUDT5
Official Full Name		Nudix Hydrolase 5
Synonym		Nudix Hydrolase 5;Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 5;YSA1H;Nuclear ATP-Synthesis Protein NUDIX5;ADP-Sugar Pyrophosphatase;8-Oxo-DGDP Phosphatase;HYSAH1;HNUDT5;EC 3.6.1.58;EC 2.7.7.96;NUDIX5;YSAH1;YSA1;Nudix Motif 5
Molecule Type		Protein coding
Position On Chromosome		chr10(Start:12165330 - End:12196144)
Strand		-
Uniprot Entry		Q9UKK9
ENSG ID		ENSG00000165609
Disease Relevance (Click to Show/Hide)
8A20: Alzheimer disease		Alzheimer's disease [Alzheimer disease]
Detailed Information		Disease Link click to show the detail information of this Disease

Metabolite(s) with this epigenetic modification
Metabolite Name: Valerate
Detailed Information	Meta Info click to show the detail information of this Metabolite	[1], [2]
Description	Valerate has been shown to hypermethylate NUDT5 CpG site in breast cancer cells.

References
1	Valerian and valeric acid inhibit growth of breast cancer cells possibly by mediating epigenetic modifications. Sci Rep. 2021 Jan 28;11(1):2519. doi: 10.1038/s41598-021-81620-x.
2	Gut Microbiota as Important Mediator Between Diet and DNA Methylation and Histone Modifications in the Host. Nutrients. 2020 Feb 25;12(3):597. doi: 10.3390/nu12030597.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.