Details of Epigenetic Molecule(EM)

General Information of EM (ID: EM11944)
Official Symbol		TRAPPC13
Official Full Name		Trafficking Protein Particle Complex Subunit 13
Synonym		Trafficking Protein Particle Complex Subunit 13;C5orf44;Trafficking Protein Particle Complex 13;Trs65-Related;FLJ13611
Molecule Type		Protein coding
Position On Chromosome		chr5(Start:65625004 - End:65666233)
Strand		+
Uniprot Entry		A5PLN9
ENSG ID		ENSG00000113597
Disease Relevance (Click to Show/Hide)
SE30: Developmental delay disorder		CHARGE and Kabuki syndromes [Developmental delay disorder]
Detailed Information		Disease Link click to show the detail information of this Disease

Metabolite(s) with this epigenetic modification
Metabolite Name: Valerate
Detailed Information	Meta Info click to show the detail information of this Metabolite	[1], [2]
Description	Valerate has been shown to hypermethylate C5orf44 CpG site in breast cancer cells.

References
1	Valerian and valeric acid inhibit growth of breast cancer cells possibly by mediating epigenetic modifications. Sci Rep. 2021 Jan 28;11(1):2519. doi: 10.1038/s41598-021-81620-x.
2	Gut Microbiota as Important Mediator Between Diet and DNA Methylation and Histone Modifications in the Host. Nutrients. 2020 Feb 25;12(3):597. doi: 10.3390/nu12030597.

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