Details of Epigenetic Molecule(EM)

General Information of EM (ID: EM10357)
Official Symbol		COQ3
Official Full Name		coenzyme Q3, methyltransferase
Synonym		bA9819.1
Molecule Type		Protein coding
Position On Chromosome		chr6(Start:99369401 - End:99394195)
Strand		-
Uniprot Entry		Q9NZJ6
ENSG ID		ENSG00000132423
Dnmivd Disease		BLCA

Metabolite(s) with this epigenetic modification
Metabolite Name: Valerate
Detailed Information	Meta Info click to show the detail information of this Metabolite	[1], [2]
Description	Valerate has been shown to hypermethylate COQ3 CpG site in breast cancer cells.

References
1	Gut Microbiota as Important Mediator Between Diet and DNA Methylation and Histone Modifications in the Host. Nutrients. 2020 Feb 25;12(3):597. doi: 10.3390/nu12030597.
2	Heterochromatinization induced by GAA-repeat hyperexpansion in Friedreich's ataxia can be reduced upon HDAC inhibition by vitamin B3. Hum Mol Genet. 2013 Jul 1;22(13):2662-75. doi: 10.1093/hmg/ddt115. Epub 2013 Mar 7.

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