Details of Epigenetic Molecule(EM)

General Information of EM (ID: EM10287)
  Official Symbol
NAXD
  Official Full Name
NAD(P)HX dehydratase
  Synonym
CARKD;FLJ10769;LP3298
  Molecule Type
Protein coding
  Position On Chromosome
chr13(Start:110615545 - End:110639996)
  Strand
+
  Uniprot Entry
Q8IW45 
  ENSG ID
ENSG00000213995 
  Dnmivd Disease
BLCA 
Metabolite(s) with this epigenetic modification
  Metabolite Name: Valerate
     Detailed Information Meta Info click to show the detail information of this Metabolite [1], [2]
     Description
Valerate has been shown to hypermethylate CARKD CpG site in breast cancer cells.

References
1 Valerian and valeric acid inhibit growth of breast cancer cells possibly by mediating epigenetic modifications. Sci Rep. 2021 Jan 28;11(1):2519. doi: 10.1038/s41598-021-81620-x.
2 Gut Microbiota as Important Mediator Between Diet and DNA Methylation and Histone Modifications in the Host. Nutrients. 2020 Feb 25;12(3):597. doi: 10.3390/nu12030597.

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