Details of Epigenetic Molecule(EM)
| General Information of EM (ID: EM09267) | |||||||
|---|---|---|---|---|---|---|---|
| Official Symbol |
CT45A4
|
||||||
| Official Full Name |
cancer/testis antigen family 45, member A4
|
||||||
| Synonym |
CT45-2;CT45-4;CT45-6;CT45.2;CT45.4;CT45.6
|
||||||
| Molecule Type |
Protein coding
|
||||||
| Position On Chromosome |
chrx(Start:134928331 - End:134953994)
|
||||||
| Strand |
-
|
||||||
| Uniprot Entry | |||||||
| ENSG ID | |||||||
| Disease Relevance (Click to Show/Hide) | |||||||
| 2A00: Primary neoplasms of brain | Glioma [Primary neoplasms of brain] | ||||||
| Detailed Information |
Disease Link
 click to show the detail information of this Disease
|
||||||
| 2A01: Primary neoplasms of meninges | Meningioma [Primary neoplasms of meninges] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 2B6B: Malignant neoplasms of nasopharynx | Nasopharyngeal carcinoma (NPC) [Malignant neoplasms of nasopharynx] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 2B70: Malignant neoplasms of oesophagus | Barrett's esophagus and esophageal adenocarcinoma [Malignant neoplasms of oesophagus] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 2B80: Malignant neoplasms of small intestine | Small intestinal neuroendocrine tumours (SINETs) [Malignant neoplasms of small intestine] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 2B90: Malignant neoplasms of colon | Colorectal cancer [Malignant neoplasms of colon] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 2C25: Malignant neoplasms of bronchus or lung | Lung cancer [Malignant neoplasms of bronchus or lung] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 2C25: Malignant neoplasms of bronchus or lung | Non small cell lung cancer (NSCLC) [Malignant neoplasms of bronchus or lung] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 2C30: Melanoma of skin | Cutaneous Melanoma [Melanoma of skin] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 2C60: Carcinoma of breast | Breast cancer [Carcinoma of breast] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 2E66: Carcinoma in situ of cervix uteri | Cervical intraepithelial neoplasia [Carcinoma in situ of cervix uteri] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 4A40: Lupus erythematosus | Systemic lupus erythematosus (SLE) [Lupus erythematosus] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 6A20: Schizophrenia | Schizophrenia [Schizophrenia] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 6E8Z: Mental, behavioural or neurodevelopmental disorders | Psychiatric disorders [Mental, behavioural or neurodevelopmental disorders] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 9A01: Infectious disorders of eyelid | Human eye and its diseases [Infectious disorders of eyelid] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| XH1E13: Germinoma | Germinoma [Germinoma] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| XH46F1: Clear cell renal cell carcinoma | Clear cell renal cell carcinoma (ccRCC) [Clear cell renal cell carcinoma] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| XH4W48: Hepatocellular carcinoma | Hepatocellular carcinoma (HCC) [Hepatocellular carcinoma] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| XH7PW5: Lymphocytic leukaemia | Pediatric acute lymphoblastic leukemia [Lymphocytic leukaemia] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| XH8SH6: CNS embryonal tumour | Primitive neuroectodermal tumors [CNS embryonal tumour] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| ZERO(Not Found): Sex chromosome anomalies | X-chromosome inactivation (XCI) [Sex chromosome anomalies] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| Protein(s) with this epigenetic modification | |||||||
|---|---|---|---|---|---|---|---|
| Protein Name: Rv2966c | |||||||
| Detailed Information |
Pro Info
click to show the detail information of this protein
|
[1] | |||||
| Description |
Rv2966c could hypermethylate the non-CpG dinucleotides at the host CT45A4 (geneBody) genetic loci during Mycobacterium tuberculosis H37Rv infection.
|
||||||
| References | |||||
|---|---|---|---|---|---|
| 1 | Genome-wide non-CpG methylation of the host genome during M. tuberculosis infection. Sci Rep. 2016 Apr 26;6:25006. doi: 10.1038/srep25006. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.