Details of Epigenetic Molecule(EM)
| General Information of EM (ID: EM09183) | |||||||
|---|---|---|---|---|---|---|---|
| Official Symbol |
PHF8
|
||||||
| Official Full Name |
PHD finger protein 8
|
||||||
| Synonym |
JHDM1F;KIAA1111;MRXSSD;ZNF422
|
||||||
| Molecule Type |
Protein coding
|
||||||
| Position On Chromosome |
chrX(Start:53936676 - End:54048958)
|
||||||
| Strand |
-
|
||||||
| Uniprot Entry | |||||||
| ENSG ID | |||||||
| Dnmivd Disease | |||||||
| Disease Relevance (Click to Show/Hide) | |||||||
| 2A00: Primary neoplasms of brain | Glioma [Primary neoplasms of brain] | ||||||
| Detailed Information |
Disease Link
 click to show the detail information of this Disease
|
||||||
| 2A01: Primary neoplasms of meninges | Meningioma [Primary neoplasms of meninges] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 2B70: Malignant neoplasms of oesophagus | Barrett's esophagus and esophageal adenocarcinoma [Malignant neoplasms of oesophagus] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 2B90: Malignant neoplasms of colon | Colorectal cancer [Malignant neoplasms of colon] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 2C12: Malignant neoplasms of liver or intrahepatic bile ducts | Liver cancer [Malignant neoplasms of liver or intrahepatic bile ducts] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 2C60: Carcinoma of breast | Breast cancer [Carcinoma of breast] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 4A40: Lupus erythematosus | Systemic lupus erythematosus (SLE) [Lupus erythematosus] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 6A00: Disorders of intellectual development | Intellectual disability and congenital anomalies(ID/CA) [Disorders of intellectual development] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 6A20: Schizophrenia | Schizophrenia [Schizophrenia] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 6C40: Disorders due to use of alcohol | Alcohol use disorder (AUD) [Disorders due to use of alcohol] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 6E8Z: Mental, behavioural or neurodevelopmental disorders | Psychiatric disorders [Mental, behavioural or neurodevelopmental disorders] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 8A20: Alzheimer disease | Alzheimer's disease [Alzheimer disease] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| 9A01: Infectious disorders of eyelid | Human eye and its diseases [Infectious disorders of eyelid] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| DB93: Hepatic fibrosis or cirrhosis | Cirrhotic [Hepatic fibrosis or cirrhosis] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| DD70: Crohn disease | Crohn's disease [Crohn disease] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| FA0Z: Osteoarthritis | Osteoarthritis (OA) [Osteoarthritis] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| FA20: Rheumatoid arthritis | Rheumatoid arthritis [Rheumatoid arthritis] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| JA24: Pre-eclampsia | Preeclampsia (PE) [Pre-eclampsia] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| LD40: Complete trisomies of the autosomes | Down syndrome (DS) [Complete trisomies of the autosomes] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| MG30: Chronic pain | Fibromyalgia [Chronic pain] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| SD86: Dementia disorder | Dementia [Dementia disorder] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| XB1Y: Familial | Familial recurrent moles (RHM) [Familial] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| XH1E13: Germinoma | Germinoma [Germinoma] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| XH3DV3: Adenoma | Adenoma [Adenoma] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| XH4W48: Hepatocellular carcinoma | Hepatocellular carcinoma (HCC) [Hepatocellular carcinoma] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| XH5QN3: Nephroblastoma | Wilms tumor [Nephroblastoma] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| XH68V1: Liver cell adenoma | Hepatocellular adenoma [Liver cell adenoma] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| XH7PW5: Lymphocytic leukaemia | Pediatric acute lymphoblastic leukemia [Lymphocytic leukaemia] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| XH7ZQ4: Atypical teratoid/rhabdoid tumour | Atypical teratoid/rhabdoid tumor (ATRT) [Atypical teratoid/rhabdoid tumour] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| XH85Z0: Neuroblastoma | Neuroblastoma [Neuroblastoma] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| XH8AA5: Acute myeloid leukaemia | Acute myeloid leukemia (AML) [Acute myeloid leukaemia] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| XH8D74: Carcinomatosis | Cancer [Carcinomatosis] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| XH8P29: Medulloblastoma | Medulloblastoma [Medulloblastoma] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| XH98Z3: Schwannoma | Schwannoma [Schwannoma] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| XN487: Human immunodeficiency virus | Human immunodeficiency virus (HIV) [Human immunodeficiency virus] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| ZERO(Not Found): Sex chromosome anomalies | X-chromosome inactivation (XCI) [Sex chromosome anomalies] | ||||||
| Detailed Information |
Disease Link
click to show the detail information of this Disease
|
||||||
| Protein(s) with this epigenetic modification | |||||||
|---|---|---|---|---|---|---|---|
| Protein Name: Rv2966c | |||||||
| Detailed Information |
Pro Info
click to show the detail information of this protein
|
[1] | |||||
| Description |
Rv2966c could hypermethylate the non-CpG dinucleotides at the host PHF8 (intergenic) genetic loci during Mycobacterium tuberculosis H37Rv infection.
|
||||||
| References | |||||
|---|---|---|---|---|---|
| 1 | Genome-wide non-CpG methylation of the host genome during M. tuberculosis infection. Sci Rep. 2016 Apr 26;6:25006. doi: 10.1038/srep25006. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.