Details of Epigenetic Molecule(EM)
| General Information of EM (ID: EM08994) | |||||||
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| Official Symbol |
POM121L10P
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| Official Full Name |
POM121 transmembrane nucleoporin like 10, pseudogene
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| Molecule Type |
Processed pseudogene
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| Position On Chromosome |
chr22(Start:24657481 - End:24658765)
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| Strand |
-
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| ENSG ID | |||||||
| NONCODE ID | |||||||
| Disease Relevance (Click to Show/Hide) | |||||||
| 2A00: Primary neoplasms of brain | Glioma [Primary neoplasms of brain] | ||||||
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| 2A90: Mature T-cell lymphoma, specified types, nodal or systemic | Anaplastic large cell lymphoma (ALCL) [Mature T-cell lymphoma, specified types, nodal or systemic] | ||||||
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| 2B6B: Malignant neoplasms of nasopharynx | Nasopharyngeal carcinoma (NPC) [Malignant neoplasms of nasopharynx] | ||||||
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| 2B6E: Malignant neoplasms of other or ill-defined sites in the lip, oral cavity or pharynx | Oral or pharyngeal squamous cell carcinoma (OPSCC) [Malignant neoplasms of other or ill-defined sites in the lip, oral cavity or pharynx] | ||||||
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| 2B70: Malignant neoplasms of oesophagus | Esophageal adenocarcinoma (EAC) [Malignant neoplasms of oesophagus] | ||||||
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| 2B90: Malignant neoplasms of colon | Colorectal cancer [Malignant neoplasms of colon] | ||||||
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| 2C25: Malignant neoplasms of bronchus or lung | Lung cancer [Malignant neoplasms of bronchus or lung] | ||||||
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| 2C25: Malignant neoplasms of bronchus or lung | Lung adenocarcinoma [Malignant neoplasms of bronchus or lung] | ||||||
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| 2C25: Malignant neoplasms of bronchus or lung | Non small cell lung cancer (NSCLC) [Malignant neoplasms of bronchus or lung] | ||||||
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| 2C30: Melanoma of skin | Cutaneous Melanoma [Melanoma of skin] | ||||||
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| 2C60: Carcinoma of breast | Breast cancer [Carcinoma of breast] | ||||||
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| 2C73: Malignant neoplasms of ovary | Ovarian carcinoma (OVCA) [Malignant neoplasms of ovary] | ||||||
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| 4A40: Lupus erythematosus | Systemic lupus erythematosus (SLE) [Lupus erythematosus] | ||||||
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| 5A72: Hyperaldosteronism | Primary aldosteronism [Hyperaldosteronism] | ||||||
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| 5B81: Obesity | Obesity [Obesity] | ||||||
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| 6E8Z: Mental, behavioural or neurodevelopmental disorders | Psychiatric disorders [Mental, behavioural or neurodevelopmental disorders] | ||||||
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| 8A01: Choreiform disorders | Huntington's disease (HD) [Choreiform disorders] | ||||||
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| 8A20: Alzheimer disease | Alzheimer's disease [Alzheimer disease] | ||||||
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| 9A01: Infectious disorders of eyelid | Human eye and its diseases [Infectious disorders of eyelid] | ||||||
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| BC81: Supraventricular tachyarrhythmia | Atrial fibrillation [Supraventricular tachyarrhythmia] | ||||||
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| BD40: Atherosclerotic chronic arterial occlusive disease | Atherosclerosis [Atherosclerotic chronic arterial occlusive disease] | ||||||
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| CA22: Chronic obstructive pulmonary disease | Chronic obstructive pulmonary disease (COPD) [Chronic obstructive pulmonary disease] | ||||||
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| DD70: Crohn disease | Crohn's disease [Crohn disease] | ||||||
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| FA20: Rheumatoid arthritis | Rheumatoid arthritis [Rheumatoid arthritis] | ||||||
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| FA21: Psoriatic arthritis | Psoriatic [Psoriatic arthritis] | ||||||
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| GA10: Endometriosis | Endometriosis [Endometriosis] | ||||||
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| JA24: Pre-eclampsia | Preeclampsia (PE) [Pre-eclampsia] | ||||||
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| LA02: Spina bifida | Neural tube defects (NTDs) [Spina bifida] | ||||||
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| LA4Z: Clefts of lip, alveolus or palate | Non-syndromic cleft lip and palate [Clefts of lip, alveolus or palate] | ||||||
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| LD2F: Syndromes with multiple structural anomalies, without predominant body system involvement | Silver russell syndrome [Syndromes with multiple structural anomalies, without predominant body system involvement] | ||||||
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| LD40: Complete trisomies of the autosomes | Down syndrome (DS) [Complete trisomies of the autosomes] | ||||||
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| SD86: Dementia disorder | Dementia [Dementia disorder] | ||||||
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| XH1E13: Germinoma | Germinoma [Germinoma] | ||||||
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| XH1XF3: Osteosarcoma | Osteosarcoma [Osteosarcoma] | ||||||
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| XH3DV3: Adenoma | Adenoma [Adenoma] | ||||||
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| XH4546: Signet ring cell carcinoma | Signet ring cell colorectal cancer [Signet ring cell carcinoma] | ||||||
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| XH4S92: Leukaemia | Leukemia [Leukaemia] | ||||||
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| XH4V32: Ductal carcinoma in situ | Ductal carcinoma in situ (DCIS) [Ductal carcinoma in situ] | ||||||
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| XH4W48: Hepatocellular carcinoma | Hepatocellular carcinoma (HCC) [Hepatocellular carcinoma] | ||||||
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| XH5QN3: Nephroblastoma | Wilms tumor [Nephroblastoma] | ||||||
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| XH68V1: Liver cell adenoma | Hepatocellular adenoma [Liver cell adenoma] | ||||||
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| XH7F82: Glioblastoma | Glioblastoma [Glioblastoma] | ||||||
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| XH7PW5: Lymphocytic leukaemia | Pediatric acute lymphoblastic leukemia [Lymphocytic leukaemia] | ||||||
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| XH85Z0: Neuroblastoma | Neuroblastoma [Neuroblastoma] | ||||||
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| XH8AA5: Acute myeloid leukaemia | Acute myeloid leukemia (AML) [Acute myeloid leukaemia] | ||||||
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| XH8P29: Medulloblastoma | Primary medulloblastoma [Medulloblastoma] | ||||||
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| XH8P29: Medulloblastoma | Medulloblastoma [Medulloblastoma] | ||||||
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| XH8SH6: CNS embryonal tumour | Primitive neuroectodermal tumors [CNS embryonal tumour] | ||||||
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| XH9HQ1: Gastrointestinal stromal tumour | Gastrointestinal stromal tumors (GIST) [Gastrointestinal stromal tumour] | ||||||
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| XN487: Human immunodeficiency virus | Human immunodeficiency virus (HIV) [Human immunodeficiency virus] | ||||||
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| Protein(s) with this epigenetic modification | |||||||
|---|---|---|---|---|---|---|---|
| Protein Name: Rv2966c | |||||||
| Detailed Information |
Pro Info
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[1] | |||||
| Description |
Rv2966c could hypermethylate the non-CpG dinucleotides at the host POM121L10P (geneBody) genetic loci during Mycobacterium tuberculosis H37Rv infection.
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| References | |||||
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| 1 | Genome-wide non-CpG methylation of the host genome during M. tuberculosis infection. Sci Rep. 2016 Apr 26;6:25006. doi: 10.1038/srep25006. | ||||
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