Details of Epigenetic Molecule(EM)
| General Information of EM (ID: EM08717) | |||||||
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| Official Symbol |
L3MBTL1
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| Official Full Name |
L3MBTL histone methyl-lysine binding protein 1
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| Synonym |
DKFZp586P1522;H-L(3)MBT;KIAA0681;L3MBT;L3MBTL;ZC2HC3;dJ138B7.3
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| Molecule Type |
Protein coding
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| Position On Chromosome |
chr20(Start:43489442 - End:43550950)
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| Strand |
+
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| Uniprot Entry | |||||||
| ENSG ID | |||||||
| Dnmivd Disease | |||||||
| Disease Relevance (Click to Show/Hide) | |||||||
| 1C62: Human immunodeficiency virus disease without mention of tuberculosis or malaria | Acquired immune deficiency syndrome [Human immunodeficiency virus disease without mention of tuberculosis or malaria] | ||||||
| Detailed Information |
Disease Link
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| 8A40: Multiple sclerosis | Multiple sclerosis [Multiple sclerosis] | ||||||
| Detailed Information |
Disease Link
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| 8E49: Postviral fatigue syndrome | Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) [Postviral fatigue syndrome] | ||||||
| Detailed Information |
Disease Link
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| DD70: Crohn disease | Crohn's disease [Crohn disease] | ||||||
| Detailed Information |
Disease Link
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| XH3DV3: Adenoma | Adenoma [Adenoma] | ||||||
| Detailed Information |
Disease Link
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| XH8P29: Medulloblastoma | Medulloblastoma [Medulloblastoma] | ||||||
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Disease Link
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| Protein(s) with this epigenetic modification | |||||||
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| Protein Name: Rv2966c | |||||||
| Detailed Information |
Pro Info
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[1] | |||||
| Description |
Rv2966c could hypermethylate the non-CpG dinucleotides at the host L3MBTL1 (intergenic) genetic loci during Mycobacterium tuberculosis H37Rv infection.
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| References | |||||
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| 1 | Genome-wide non-CpG methylation of the host genome during M. tuberculosis infection. Sci Rep. 2016 Apr 26;6:25006. doi: 10.1038/srep25006. | ||||
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