Details of Epigenetic Molecule(EM)
| General Information of EM (ID: EM08236) | |||||||
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| Official Symbol |
PSMG2
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| Official Full Name |
proteasome assembly chaperone 2
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| Synonym |
CLAST3;HCCA3;HsT1707;MDS003;MGC15092;PAC2;TNFSF5IP1
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| Molecule Type |
Protein coding
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| Position On Chromosome |
chr18(Start:12658043 - End:12725740)
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| Strand |
+
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| Uniprot Entry | |||||||
| ENSG ID | |||||||
| Dnmivd Disease | |||||||
| Disease Relevance (Click to Show/Hide) | |||||||
| 1C62: Human immunodeficiency virus disease without mention of tuberculosis or malaria | Acquired immune deficiency syndrome [Human immunodeficiency virus disease without mention of tuberculosis or malaria] | ||||||
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| 2A01: Primary neoplasms of meninges | Meningioma [Primary neoplasms of meninges] | ||||||
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| 2B90: Malignant neoplasms of colon | Colorectal cancer [Malignant neoplasms of colon] | ||||||
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| 2C60: Carcinoma of breast | Breast cancer [Carcinoma of breast] | ||||||
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| 2D10: Malignant neoplasms of thyroid gland | Thyroid tumors [Malignant neoplasms of thyroid gland] | ||||||
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| 4A40: Lupus erythematosus | Systemic lupus erythematosus (SLE) [Lupus erythematosus] | ||||||
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| 4A40: Lupus erythematosus | Lupus [Lupus erythematosus] | ||||||
| Detailed Information |
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| 5B81: Obesity | Obesity [Obesity] | ||||||
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| 6A20: Schizophrenia | Schizophrenia [Schizophrenia] | ||||||
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| 6E8Z: Mental, behavioural or neurodevelopmental disorders | Psychiatric disorders [Mental, behavioural or neurodevelopmental disorders] | ||||||
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| 8A20: Alzheimer disease | Alzheimer's disease [Alzheimer disease] | ||||||
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| 8A40: Multiple sclerosis | Multiple sclerosis [Multiple sclerosis] | ||||||
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| 9A01: Infectious disorders of eyelid | Human eye and its diseases [Infectious disorders of eyelid] | ||||||
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| GA10: Endometriosis | Endometriosis [Endometriosis] | ||||||
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| LA02: Spina bifida | Neural tube defects (NTDs) [Spina bifida] | ||||||
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| LD2FZERO(Not Found)0: Toxic or drug-related embryofetopathies | Fetal alcohol syndrome (FAS) [Toxic or drug-related embryofetopathies] | ||||||
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| XH0945: Squamous cell carcinoma | Head and neck squamous cell cancer (HNSCC) [Squamous cell carcinoma] | ||||||
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| XH1E13: Germinoma | Germinoma [Germinoma] | ||||||
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| XH4W48: Hepatocellular carcinoma | Hepatocellular carcinoma (HCC) [Hepatocellular carcinoma] | ||||||
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| XH7F82: Glioblastoma | Glioblastoma [Glioblastoma] | ||||||
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| XH7PW5: Lymphocytic leukaemia | Pediatric acute lymphoblastic leukemia [Lymphocytic leukaemia] | ||||||
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| XH7ZQ4: Atypical teratoid/rhabdoid tumour | Atypical teratoid/rhabdoid tumor (ATRT) [Atypical teratoid/rhabdoid tumour] | ||||||
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| XH85Z0: Neuroblastoma | Neuroblastoma [Neuroblastoma] | ||||||
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| XH8AA5: Acute myeloid leukaemia | Acute myeloid leukemia (AML) [Acute myeloid leukaemia] | ||||||
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| XH8P29: Medulloblastoma | Medulloblastoma [Medulloblastoma] | ||||||
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| XH9HQ1: Gastrointestinal stromal tumour | Gastrointestinal stromal tumors (GIST) [Gastrointestinal stromal tumour] | ||||||
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| Protein(s) with this epigenetic modification | |||||||
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| Protein Name: Rv2966c | |||||||
| Detailed Information |
Pro Info
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[1] | |||||
| Description |
Rv2966c could hypermethylate the non-CpG dinucleotides at the host PSMG2 (geneBody) genetic loci during Mycobacterium tuberculosis H37Rv infection.
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| Protein Name: Rv2966c | |||||||
| Detailed Information |
Pro Info
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|
[1] | |||||
| Description |
Rv2966c could hypermethylate the non-CpG dinucleotides at the host PSMG2 (intergenic) genetic loci during Mycobacterium tuberculosis H37Rv infection.
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| References | |||||
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| 1 | Genome-wide non-CpG methylation of the host genome during M. tuberculosis infection. Sci Rep. 2016 Apr 26;6:25006. doi: 10.1038/srep25006. | ||||
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