Details of Epigenetic Molecule(EM)
| General Information of EM (ID: EM08109) | |||||||
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| Official Symbol |
SKA2
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| Official Full Name |
spindle and kinetochore associated complex subunit 2
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| Molecule Type |
Protein coding
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| Position On Chromosome |
chr17(Start:59109857 - End:59155260)
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| Strand |
-
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| Uniprot Entry | |||||||
| ENSG ID | |||||||
| Dnmivd Disease | |||||||
| Disease Relevance (Click to Show/Hide) | |||||||
| 2C25: Malignant neoplasms of bronchus or lung | Non small cell lung cancer (NSCLC) [Malignant neoplasms of bronchus or lung] | ||||||
| Detailed Information |
Disease Link
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| 6A20: Schizophrenia | Schizophrenia [Schizophrenia] | ||||||
| Detailed Information |
Disease Link
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| 9A01: Infectious disorders of eyelid | Human eye and its diseases [Infectious disorders of eyelid] | ||||||
| Detailed Information |
Disease Link
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| XH1XF3: Osteosarcoma | Osteosarcoma [Osteosarcoma] | ||||||
| Detailed Information |
Disease Link
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| XH8AA5: Acute myeloid leukaemia | Acute myeloid leukemia (AML) [Acute myeloid leukaemia] | ||||||
| Detailed Information |
Disease Link
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| XH8P29: Medulloblastoma | Medulloblastoma [Medulloblastoma] | ||||||
| Detailed Information |
Disease Link
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| XN487: Human immunodeficiency virus | Human immunodeficiency virus (HIV) [Human immunodeficiency virus] | ||||||
| Detailed Information |
Disease Link
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| Protein(s) with this epigenetic modification | |||||||
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| Protein Name: Rv2966c | |||||||
| Detailed Information |
Pro Info
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[1] | |||||
| Description |
Rv2966c could hypermethylate the non-CpG dinucleotides at the host SKA2 (geneBody) genetic loci during Mycobacterium tuberculosis H37Rv infection.
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| References | |||||
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| 1 | Genome-wide non-CpG methylation of the host genome during M. tuberculosis infection. Sci Rep. 2016 Apr 26;6:25006. doi: 10.1038/srep25006. | ||||
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