Details of Epigenetic Molecule(EM)
| General Information of EM (ID: EM08046) | |||||||
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| Official Symbol |
KRTAP9-9
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| Official Full Name |
keratin associated protein 9-9
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| Molecule Type |
Protein coding
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| Position On Chromosome |
chr17(Start:41255384 - End:41256364)
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| Strand |
+
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| Uniprot Entry | |||||||
| ENSG ID | |||||||
| Dnmivd Disease | |||||||
| Disease Relevance (Click to Show/Hide) | |||||||
| 1B10: Tuberculosis of the respiratory system | Tuberculosis (TB) [Tuberculosis of the respiratory system] | ||||||
| Detailed Information |
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| 2A00: Primary neoplasms of brain | Glioma [Primary neoplasms of brain] | ||||||
| Detailed Information |
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| 2B90: Malignant neoplasms of colon | Colorectal cancer [Malignant neoplasms of colon] | ||||||
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| 2C25: Malignant neoplasms of bronchus or lung | Non small cell lung cancer (NSCLC) [Malignant neoplasms of bronchus or lung] | ||||||
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| 2C60: Carcinoma of breast | Breast cancer [Carcinoma of breast] | ||||||
| Detailed Information |
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| 8A20: Alzheimer disease | Alzheimer's disease [Alzheimer disease] | ||||||
| Detailed Information |
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| 8A40: Multiple sclerosis | Multiple sclerosis [Multiple sclerosis] | ||||||
| Detailed Information |
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| 9A01: Infectious disorders of eyelid | Human eye and its diseases [Infectious disorders of eyelid] | ||||||
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| CA22: Chronic obstructive pulmonary disease | Chronic obstructive pulmonary disease (COPD) [Chronic obstructive pulmonary disease] | ||||||
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| DB92: Non-alcoholic fatty liver disease | Nonalcoholic fatty liver disease (NAFLD) [Non-alcoholic fatty liver disease] | ||||||
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| GA10: Endometriosis | Endometriosis [Endometriosis] | ||||||
| Detailed Information |
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| LA4Z: Clefts of lip, alveolus or palate | Non-syndromic cleft lip and palate [Clefts of lip, alveolus or palate] | ||||||
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| SE30: Developmental delay disorder | CHARGE and Kabuki syndromes [Developmental delay disorder] | ||||||
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| XH1E13: Germinoma | Germinoma [Germinoma] | ||||||
| Detailed Information |
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| XH1XF3: Osteosarcoma | Osteosarcoma [Osteosarcoma] | ||||||
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| XH3DV3: Adenoma | Adenoma [Adenoma] | ||||||
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| XH4S92: Leukaemia | Leukemia [Leukaemia] | ||||||
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| XH4W48: Hepatocellular carcinoma | Hepatocellular carcinoma (HCC) [Hepatocellular carcinoma] | ||||||
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| XH7PW5: Lymphocytic leukaemia | Pediatric acute lymphoblastic leukemia [Lymphocytic leukaemia] | ||||||
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| XH7ZQ4: Atypical teratoid/rhabdoid tumour | Atypical teratoid/rhabdoid tumor (ATRT) [Atypical teratoid/rhabdoid tumour] | ||||||
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| XH8AA5: Acute myeloid leukaemia | Acute myeloid leukemia (AML) [Acute myeloid leukaemia] | ||||||
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| XH8D74: Carcinomatosis | Cancer [Carcinomatosis] | ||||||
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| XH8P29: Medulloblastoma | Medulloblastoma [Medulloblastoma] | ||||||
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| XH8SH6: CNS embryonal tumour | Primitive neuroectodermal tumors [CNS embryonal tumour] | ||||||
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| XH9HQ1: Gastrointestinal stromal tumour | Gastrointestinal stromal tumors (GIST) [Gastrointestinal stromal tumour] | ||||||
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| Protein(s) with this epigenetic modification | |||||||
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| Protein Name: Rv2966c | |||||||
| Detailed Information |
Pro Info
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[1] | |||||
| Description |
Rv2966c could hypermethylate the non-CpG dinucleotides at the host KRTAP9-9 (TSS) genetic loci during Mycobacterium tuberculosis H37Rv infection.
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| References | |||||
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| 1 | Genome-wide non-CpG methylation of the host genome during M. tuberculosis infection. Sci Rep. 2016 Apr 26;6:25006. doi: 10.1038/srep25006. | ||||
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