General Information of EM (ID: EM07591)
  Official Symbol
BBS4
  Official Full Name
Bardet-Biedl syndrome 4
  Molecule Type
Protein coding
  Position On Chromosome
chr15(Start:72686179 - End:72738475)
  Strand
+
  Uniprot Entry
Q96RK4 
  ENSG ID
ENSG00000140463 
  Dnmivd Disease
KIRC 
    Disease Relevance (Click to Show/Hide)
         2B6B: Malignant neoplasms of nasopharynx Nasopharyngeal carcinoma (NPC) [Malignant neoplasms of nasopharynx]
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         2B80: Malignant neoplasms of small intestine Small intestinal neuroendocrine tumours (SINETs) [Malignant neoplasms of small intestine]
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         2B90: Malignant neoplasms of colon Colorectal cancer [Malignant neoplasms of colon]
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         2C60: Carcinoma of breast Breast cancer [Carcinoma of breast]
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         4A40: Lupus erythematosus Systemic lupus erythematosus (SLE) [Lupus erythematosus]
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         6A20: Schizophrenia Schizophrenia [Schizophrenia]
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         8A20: Alzheimer disease Alzheimer's disease [Alzheimer disease]
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         8A40: Multiple sclerosis Multiple sclerosis [Multiple sclerosis]
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         8E49: Postviral fatigue syndrome Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) [Postviral fatigue syndrome]
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         9A01: Infectious disorders of eyelid Human eye and its diseases [Infectious disorders of eyelid]
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         GA10: Endometriosis Endometriosis [Endometriosis]
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         JA24: Pre-eclampsia Preeclampsia (PE) [Pre-eclampsia]
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         LA02: Spina bifida Neural tube defects (NTDs) [Spina bifida]
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         XH1E13: Germinoma Germinoma [Germinoma]
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         XH3DV3: Adenoma Adenoma [Adenoma]
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         XH4546: Signet ring cell carcinoma Signet ring cell colorectal cancer [Signet ring cell carcinoma]
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         XH4S92: Leukaemia Leukemia [Leukaemia]
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         XH7F82: Glioblastoma Glioblastoma [Glioblastoma]
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         XH7PW5: Lymphocytic leukaemia Pediatric acute lymphoblastic leukemia [Lymphocytic leukaemia]
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         XH85Z0: Neuroblastoma Neuroblastoma [Neuroblastoma]
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         XH8AA5: Acute myeloid leukaemia Acute myeloid leukemia (AML) [Acute myeloid leukaemia]
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         XH8P29: Medulloblastoma Medulloblastoma [Medulloblastoma]
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         XH94U0: Pituitary adenoma Nonfunctioning pituitary adenomas [Pituitary adenoma]
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         XH9HQ1: Gastrointestinal stromal tumour Gastrointestinal stromal tumors (GIST) [Gastrointestinal stromal tumour]
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         XN487: Human immunodeficiency virus Human immunodeficiency virus (HIV) [Human immunodeficiency virus]
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Protein(s) with this epigenetic modification
  Protein Name: Rv2966c
     Detailed Information Pro Info click to show the detail information of this protein [1]
     Description
Rv2966c could hypermethylate the non-CpG dinucleotides at the host BBS4 (geneBody) genetic loci during Mycobacterium tuberculosis H37Rv infection.
  Protein Name: Rv2966c
     Detailed Information Pro Info click to show the detail information of this protein [1]
     Description
Rv2966c could hypomethylate the non-CpG dinucleotides at the host BBS4 (geneBody) genetic loci during Mycobacterium tuberculosis H37Rv infection.

References
1 Genome-wide non-CpG methylation of the host genome during M. tuberculosis infection. Sci Rep. 2016 Apr 26;6:25006. doi: 10.1038/srep25006.

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