Details of Epigenetic Molecule(EM)
| General Information of EM (ID: EM07219) | |||||||
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| Official Symbol |
FCF1
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| Official Full Name |
FCF1 rRNA-processing protein
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| Synonym |
Bka;C14orf111;CGI-35;UTP24
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| Molecule Type |
Protein coding
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| Position On Chromosome |
chr14(Start:74713144 - End:74738620)
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| Strand |
+
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| Uniprot Entry | |||||||
| ENSG ID | |||||||
| Dnmivd Disease | |||||||
| Disease Relevance (Click to Show/Hide) | |||||||
| 1F84: Opisthorchiasis | Opisthorchis viverrini [Opisthorchiasis] | ||||||
| Detailed Information |
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| 2A01: Primary neoplasms of meninges | Meningioma [Primary neoplasms of meninges] | ||||||
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| 2B6B: Malignant neoplasms of nasopharynx | Nasopharyngeal carcinoma (NPC) [Malignant neoplasms of nasopharynx] | ||||||
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| 2B90: Malignant neoplasms of colon | Colon adenocarcinoma [Malignant neoplasms of colon] | ||||||
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| 2B90: Malignant neoplasms of colon | Colorectal cancer [Malignant neoplasms of colon] | ||||||
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| 2C10: Malignant neoplasm of pancreas | Pancreatic ductal adenocarcinoma (PDAC) [Malignant neoplasm of pancreas] | ||||||
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| 2C12: Malignant neoplasms of liver or intrahepatic bile ducts | Liver cancer [Malignant neoplasms of liver or intrahepatic bile ducts] | ||||||
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| 2C25: Malignant neoplasms of bronchus or lung | Non small cell lung cancer (NSCLC) [Malignant neoplasms of bronchus or lung] | ||||||
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| 2C60: Carcinoma of breast | Breast cancer [Carcinoma of breast] | ||||||
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| 2D10: Malignant neoplasms of thyroid gland | Thyroid tumors [Malignant neoplasms of thyroid gland] | ||||||
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| 4A40: Lupus erythematosus | Systemic lupus erythematosus (SLE) [Lupus erythematosus] | ||||||
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| 6E8Z: Mental, behavioural or neurodevelopmental disorders | Psychiatric disorders [Mental, behavioural or neurodevelopmental disorders] | ||||||
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| 8A20: Alzheimer disease | Alzheimer's disease [Alzheimer disease] | ||||||
| Detailed Information |
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| 9A01: Infectious disorders of eyelid | Human eye and its diseases [Infectious disorders of eyelid] | ||||||
| Detailed Information |
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| BD40: Atherosclerotic chronic arterial occlusive disease | Atherosclerosis [Atherosclerotic chronic arterial occlusive disease] | ||||||
| Detailed Information |
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| DD70: Crohn disease | Crohn's disease [Crohn disease] | ||||||
| Detailed Information |
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| FA20: Rheumatoid arthritis | Rheumatoid arthritis [Rheumatoid arthritis] | ||||||
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| GA10: Endometriosis | Endometriosis [Endometriosis] | ||||||
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| LA4Z: Clefts of lip, alveolus or palate | Non-syndromic cleft lip and palate [Clefts of lip, alveolus or palate] | ||||||
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| LD40: Complete trisomies of the autosomes | Down syndrome (DS) [Complete trisomies of the autosomes] | ||||||
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| LD44: Deletions of the autosomes | Deletion or duplication of chromosome 7q11.23 [Deletions of the autosomes] | ||||||
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| SE30: Developmental delay disorder | CHARGE and Kabuki syndromes [Developmental delay disorder] | ||||||
| Detailed Information |
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| XB8M: Congenital | Melanoma [Congenital] | ||||||
| Detailed Information |
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| XH1E13: Germinoma | Germinoma [Germinoma] | ||||||
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| XH4S92: Leukaemia | Leukemia [Leukaemia] | ||||||
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| XH4V32: Ductal carcinoma in situ | Ductal carcinoma in situ (DCIS) [Ductal carcinoma in situ] | ||||||
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| XH4W48: Hepatocellular carcinoma | Hepatocellular carcinoma (HCC) [Hepatocellular carcinoma] | ||||||
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| XH7PW5: Lymphocytic leukaemia | Pediatric acute lymphoblastic leukemia [Lymphocytic leukaemia] | ||||||
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| XH85Z0: Neuroblastoma | Neuroblastoma [Neuroblastoma] | ||||||
| Detailed Information |
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| XH8AA5: Acute myeloid leukaemia | Acute myeloid leukemia (AML) [Acute myeloid leukaemia] | ||||||
| Detailed Information |
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| XH8P29: Medulloblastoma | Medulloblastoma [Medulloblastoma] | ||||||
| Detailed Information |
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| XH8P29: Medulloblastoma | Primary medulloblastoma [Medulloblastoma] | ||||||
| Detailed Information |
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| XH9HQ1: Gastrointestinal stromal tumour | Gastrointestinal stromal tumors (GIST) [Gastrointestinal stromal tumour] | ||||||
| Detailed Information |
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| XN487: Human immunodeficiency virus | Human immunodeficiency virus (HIV) [Human immunodeficiency virus] | ||||||
| Detailed Information |
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| ZERO(Not Found): Acute mania and inflammatory | Acute mania and inflammatory [Acute mania and inflammatory] | ||||||
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| Protein(s) with this epigenetic modification | |||||||
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| Protein Name: Rv2966c | |||||||
| Detailed Information |
Pro Info
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[1] | |||||
| Description |
Rv2966c could hypermethylate the non-CpG dinucleotides at the host FCF1 (geneBody) genetic loci during Mycobacterium tuberculosis H37Rv infection.
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| References | |||||
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| 1 | Genome-wide non-CpG methylation of the host genome during M. tuberculosis infection. Sci Rep. 2016 Apr 26;6:25006. doi: 10.1038/srep25006. | ||||
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