Details of Epigenetic Molecule(EM)
| General Information of EM (ID: EM06833) | |||||||
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| Official Symbol |
GPALPP1
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| Official Full Name |
GPALPP motifs containing 1
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| Synonym |
AD029;bA245H20.2;KIAA1704;LSR7
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| Molecule Type |
Protein coding
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| Position On Chromosome |
chr13(Start:44989529 - End:45037669)
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| Strand |
+
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| Uniprot Entry | |||||||
| ENSG ID | |||||||
| Dnmivd Disease | |||||||
| Disease Relevance (Click to Show/Hide) | |||||||
| 2A00: Primary neoplasms of brain | Glioma [Primary neoplasms of brain] | ||||||
| Detailed Information |
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| 2A01: Primary neoplasms of meninges | Meningioma [Primary neoplasms of meninges] | ||||||
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| 2A90: Mature T-cell lymphoma, specified types, nodal or systemic | Anaplastic large cell lymphoma (ALCL) [Mature T-cell lymphoma, specified types, nodal or systemic] | ||||||
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| 2B70: Malignant neoplasms of oesophagus | Barrett's esophagus and esophageal adenocarcinoma [Malignant neoplasms of oesophagus] | ||||||
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| 2B70: Malignant neoplasms of oesophagus | Esophageal adenocarcinoma (EAC) [Malignant neoplasms of oesophagus] | ||||||
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| 2C25: Malignant neoplasms of bronchus or lung | Lung cancer [Malignant neoplasms of bronchus or lung] | ||||||
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| 2C25: Malignant neoplasms of bronchus or lung | Non small cell lung cancer (NSCLC) [Malignant neoplasms of bronchus or lung] | ||||||
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| 2C60: Carcinoma of breast | Breast cancer [Carcinoma of breast] | ||||||
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| 2D10: Malignant neoplasms of thyroid gland | Thyroid tumors [Malignant neoplasms of thyroid gland] | ||||||
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| 2E66: Carcinoma in situ of cervix uteri | Cervical squamous cell carcinoma [Carcinoma in situ of cervix uteri] | ||||||
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| 5B81: Obesity | Obesity [Obesity] | ||||||
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| 6E8Z: Mental, behavioural or neurodevelopmental disorders | Psychiatric disorders [Mental, behavioural or neurodevelopmental disorders] | ||||||
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| 8A20: Alzheimer disease | Alzheimer's disease [Alzheimer disease] | ||||||
| Detailed Information |
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| BC20: Chronic rheumatic heart diseases, not elsewhere classified | Rheumatic heart disease (RHD) [Chronic rheumatic heart diseases, not elsewhere classified] | ||||||
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| FA20: Rheumatoid arthritis | Rheumatoid arthritis [Rheumatoid arthritis] | ||||||
| Detailed Information |
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| GA10: Endometriosis | Endometriosis [Endometriosis] | ||||||
| Detailed Information |
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| JA24: Pre-eclampsia | Preeclampsia (PE) [Pre-eclampsia] | ||||||
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| LD2C: Overgrowth syndromes | Sotos syndrome(SS) [Overgrowth syndromes] | ||||||
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| XB8M: Congenital | Melanoma [Congenital] | ||||||
| Detailed Information |
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| XH1E13: Germinoma | Germinoma [Germinoma] | ||||||
| Detailed Information |
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| XH1ND9: Papillary carcinoma of thyroid | Papillary thyroid carcinoma [Papillary carcinoma of thyroid] | ||||||
| Detailed Information |
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| XH3DV3: Adenoma | Adenoma [Adenoma] | ||||||
| Detailed Information |
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| XH4546: Signet ring cell carcinoma | Signet ring cell colorectal cancer [Signet ring cell carcinoma] | ||||||
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| XH6PH6: Astrocytoma | Astrocytoma [Astrocytoma] | ||||||
| Detailed Information |
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| XH7F82: Glioblastoma | Glioblastoma [Glioblastoma] | ||||||
| Detailed Information |
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| XH8AA5: Acute myeloid leukaemia | Acute myeloid leukemia (AML) [Acute myeloid leukaemia] | ||||||
| Detailed Information |
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| XH8P29: Medulloblastoma | Medulloblastoma [Medulloblastoma] | ||||||
| Detailed Information |
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| XH8SH6: CNS embryonal tumour | Primitive neuroectodermal tumors [CNS embryonal tumour] | ||||||
| Detailed Information |
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| XH94U0: Pituitary adenoma | Nonfunctioning pituitary adenomas [Pituitary adenoma] | ||||||
| Detailed Information |
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| XH9HQ1: Gastrointestinal stromal tumour | Gastrointestinal stromal tumors (GIST) [Gastrointestinal stromal tumour] | ||||||
| Detailed Information |
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| XN487: Human immunodeficiency virus | Human immunodeficiency virus (HIV) [Human immunodeficiency virus] | ||||||
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| Protein(s) with this epigenetic modification | |||||||
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| Protein Name: Rv2966c | |||||||
| Detailed Information |
Pro Info
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[1] | |||||
| Description |
Rv2966c could hypermethylate the non-CpG dinucleotides at the host KIAA1704 (geneBody) genetic loci during Mycobacterium tuberculosis H37Rv infection.
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| Protein Name: Rv2966c | |||||||
| Detailed Information |
Pro Info
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|
[1] | |||||
| Description |
Rv2966c could hypomethylate the non-CpG dinucleotides at the host KIAA1704 (intergenic) genetic loci during Mycobacterium tuberculosis H37Rv infection.
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| References | |||||
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| 1 | Genome-wide non-CpG methylation of the host genome during M. tuberculosis infection. Sci Rep. 2016 Apr 26;6:25006. doi: 10.1038/srep25006. | ||||
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