Details of Epigenetic Molecule(EM)
| General Information of EM (ID: EM06762) | |||||||
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| Official Symbol |
RPL21
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| Official Full Name |
ribosomal protein L21
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| Synonym |
DKFZp686C06101;FLJ27458;L21;MGC104274;MGC104275;MGC71252
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| Molecule Type |
Protein coding
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| Position On Chromosome |
chr13(Start:27251309 - End:27256691)
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| Strand |
+
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| Uniprot Entry | |||||||
| ENSG ID | |||||||
| Dnmivd Disease | |||||||
| Disease Relevance (Click to Show/Hide) | |||||||
| 2A01: Primary neoplasms of meninges | Meningioma [Primary neoplasms of meninges] | ||||||
| Detailed Information |
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| 2B90: Malignant neoplasms of colon | Colon adenocarcinoma [Malignant neoplasms of colon] | ||||||
| Detailed Information |
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| 2C60: Carcinoma of breast | Breast cancer [Carcinoma of breast] | ||||||
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| 4A40: Lupus erythematosus | Systemic lupus erythematosus (SLE) [Lupus erythematosus] | ||||||
| Detailed Information |
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| 8A20: Alzheimer disease | Alzheimer's disease [Alzheimer disease] | ||||||
| Detailed Information |
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| FA20: Rheumatoid arthritis | Rheumatoid arthritis [Rheumatoid arthritis] | ||||||
| Detailed Information |
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| SD86: Dementia disorder | Dementia [Dementia disorder] | ||||||
| Detailed Information |
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| XB8M: Congenital | Melanoma [Congenital] | ||||||
| Detailed Information |
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| XH1E13: Germinoma | Germinoma [Germinoma] | ||||||
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| XH3DV3: Adenoma | Adenoma [Adenoma] | ||||||
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| XH46F1: Clear cell renal cell carcinoma | Clear cell renal cell carcinoma (ccRCC) [Clear cell renal cell carcinoma] | ||||||
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| XH7ZQ4: Atypical teratoid/rhabdoid tumour | Atypical teratoid/rhabdoid tumor (ATRT) [Atypical teratoid/rhabdoid tumour] | ||||||
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| XH85Z0: Neuroblastoma | Neuroblastoma [Neuroblastoma] | ||||||
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| XH8AA5: Acute myeloid leukaemia | Acute myeloid leukemia (AML) [Acute myeloid leukaemia] | ||||||
| Detailed Information |
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| XH8P29: Medulloblastoma | Medulloblastoma [Medulloblastoma] | ||||||
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| Protein(s) with this epigenetic modification | |||||||
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| Protein Name: Rv2966c | |||||||
| Detailed Information |
Pro Info
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[1] | |||||
| Description |
Rv2966c could hypermethylate the non-CpG dinucleotides at the host RPL21 (intergenic) genetic loci during Mycobacterium tuberculosis H37Rv infection.
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| References | |||||
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| 1 | Genome-wide non-CpG methylation of the host genome during M. tuberculosis infection. Sci Rep. 2016 Apr 26;6:25006. doi: 10.1038/srep25006. | ||||
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