General Information of EM (ID: EM06130)
  Official Symbol
FAM76B
  Official Full Name
family with sequence similarity 76 member B
  Synonym
MGC33371
  Molecule Type
Protein coding
  Position On Chromosome
chr11(Start:95768953 - End:95790409)
  Strand
-
  Uniprot Entry
F5GX09 
  ENSG ID
ENSG00000077458 
  Dnmivd Disease
LUSC 
    Disease Relevance (Click to Show/Hide)
         1B10: Tuberculosis of the respiratory system Tuberculosis (TB) [Tuberculosis of the respiratory system]
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         2A01: Primary neoplasms of meninges Meningioma [Primary neoplasms of meninges]
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         2B70: Malignant neoplasms of oesophagus Esophageal adenocarcinoma (EAC) [Malignant neoplasms of oesophagus]
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         2B90: Malignant neoplasms of colon Colon adenocarcinoma [Malignant neoplasms of colon]
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         2C60: Carcinoma of breast Breast cancer [Carcinoma of breast]
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         6A20: Schizophrenia Schizophrenia [Schizophrenia]
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         6E8Z: Mental, behavioural or neurodevelopmental disorders Psychiatric disorders [Mental, behavioural or neurodevelopmental disorders]
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         8A00: Parkinsonism Parkinson's disease (PD) [Parkinsonism]
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         8A20: Alzheimer disease Alzheimer's disease [Alzheimer disease]
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         FA20: Rheumatoid arthritis Rheumatoid arthritis [Rheumatoid arthritis]
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         GA10: Endometriosis Endometriosis [Endometriosis]
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         LD2C: Overgrowth syndromes Sotos syndrome(SS) [Overgrowth syndromes]
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         LD44: Deletions of the autosomes Deletion or duplication of chromosome 7q11.23 [Deletions of the autosomes]
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         MG22: Fatigue Chronic fatigue syndrome (CFS) [Fatigue]
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         XH1E13: Germinoma Germinoma [Germinoma]
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         XH3DV3: Adenoma Adenoma [Adenoma]
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         XH4S92: Leukaemia Leukemia [Leukaemia]
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         XH7F82: Glioblastoma Glioblastoma [Glioblastoma]
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         XH85Z0: Neuroblastoma Neuroblastoma [Neuroblastoma]
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         XH8AA5: Acute myeloid leukaemia Acute myeloid leukemia (AML) [Acute myeloid leukaemia]
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         XH8P29: Medulloblastoma Medulloblastoma [Medulloblastoma]
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         XH8P29: Medulloblastoma Primary medulloblastoma [Medulloblastoma]
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         XH8SH6: CNS embryonal tumour Primitive neuroectodermal tumors [CNS embryonal tumour]
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         XH9HQ1: Gastrointestinal stromal tumour Gastrointestinal stromal tumors (GIST) [Gastrointestinal stromal tumour]
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         XN487: Human immunodeficiency virus Human immunodeficiency virus (HIV) [Human immunodeficiency virus]
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Protein(s) with this epigenetic modification
  Protein Name: Rv2966c
     Detailed Information Pro Info click to show the detail information of this protein [1]
     Description
Rv2966c could hypermethylate the non-CpG dinucleotides at the host FAM76B (intergenic) genetic loci during Mycobacterium tuberculosis H37Rv infection.
  Protein Name: Rv2966c
     Detailed Information Pro Info click to show the detail information of this protein [1]
     Description
Rv2966c could hypomethylate the non-CpG dinucleotides at the host FAM76B (intergenic) genetic loci during Mycobacterium tuberculosis H37Rv infection.

References
1 Genome-wide non-CpG methylation of the host genome during M. tuberculosis infection. Sci Rep. 2016 Apr 26;6:25006. doi: 10.1038/srep25006.

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