General Information of EM (ID: EM06116)
  Official Symbol
SMCO4
  Official Full Name
single-pass membrane protein with coiled-coil domains 4
  Molecule Type
Protein coding
  Position On Chromosome
chr11(Start:93478472 - End:93543391)
  Strand
-
  Uniprot Entry
A0A024R3A3 
  ENSG ID
ENSG00000166002 
  Dnmivd Disease
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    Disease Relevance (Click to Show/Hide)
         1C62: Human immunodeficiency virus disease without mention of tuberculosis or malaria Acquired immune deficiency syndrome [Human immunodeficiency virus disease without mention of tuberculosis or malaria]
            Detailed Information Disease Link click to show the detail information of this Disease
         8A40: Multiple sclerosis Multiple sclerosis [Multiple sclerosis]
            Detailed Information Disease Link click to show the detail information of this Disease
         8E49: Postviral fatigue syndrome Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) [Postviral fatigue syndrome]
            Detailed Information Disease Link click to show the detail information of this Disease
         DD70: Crohn disease Crohn's disease [Crohn disease]
            Detailed Information Disease Link click to show the detail information of this Disease
         XH3DV3: Adenoma Adenoma [Adenoma]
            Detailed Information Disease Link click to show the detail information of this Disease
         XH8P29: Medulloblastoma Medulloblastoma [Medulloblastoma]
            Detailed Information Disease Link click to show the detail information of this Disease
Protein(s) with this epigenetic modification
  Protein Name: Rv2966c
     Detailed Information Pro Info click to show the detail information of this protein [1]
     Description
Rv2966c could hypermethylate the non-CpG dinucleotides at the host SMCO4 (intergenic) genetic loci during Mycobacterium tuberculosis H37Rv infection.
  Protein Name: Rv2966c
     Detailed Information Pro Info click to show the detail information of this protein [1]
     Description
Rv2966c could hypomethylate the non-CpG dinucleotides at the host SMCO4 (geneBody) genetic loci during Mycobacterium tuberculosis H37Rv infection.

References
1 Genome-wide non-CpG methylation of the host genome during M. tuberculosis infection. Sci Rep. 2016 Apr 26;6:25006. doi: 10.1038/srep25006.

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