Details of Epigenetic Molecule(EM)

General Information of EM (ID: EM04248)
  Official Symbol
GSAP
  Official Full Name
gamma-secretase activating protein
  Molecule Type
Protein coding
  Position On Chromosome
chr7(Start:77310751 - End:77416349)
  Strand
-
  Uniprot Entry
A4D1B5 
  ENSG ID
ENSG00000186088 
  Dnmivd Disease
UCEC 
    Disease Relevance (Click to Show/Hide)
         8A40: Multiple sclerosis Multiple sclerosis [Multiple sclerosis]
            Detailed Information Disease Link click to show the detail information of this Disease
         8E49: Postviral fatigue syndrome Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) [Postviral fatigue syndrome]
            Detailed Information Disease Link click to show the detail information of this Disease
         DD70: Crohn disease Crohn's disease [Crohn disease]
            Detailed Information Disease Link click to show the detail information of this Disease
         XH3DV3: Adenoma Adenoma [Adenoma]
            Detailed Information Disease Link click to show the detail information of this Disease
         XH8P29: Medulloblastoma Medulloblastoma [Medulloblastoma]
            Detailed Information Disease Link click to show the detail information of this Disease
Protein(s) with this epigenetic modification
  Protein Name: Rv2966c
     Detailed Information Pro Info click to show the detail information of this protein [1]
     Description
Rv2966c could hypermethylate the non-CpG dinucleotides at the host GSAP (geneBody) genetic loci during Mycobacterium tuberculosis H37Rv infection.

References
1 Genome-wide non-CpG methylation of the host genome during M. tuberculosis infection. Sci Rep. 2016 Apr 26;6:25006. doi: 10.1038/srep25006.

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