General Information of EM (ID: EM03252)
  Official Symbol
ANKHD1-EIF4EBP3
  Official Full Name
ANKHD1-EIF4EBP3 readthrough
  Molecule Type
Protein coding
  Position On Chromosome
chr5(Start:140401908 - End:140549569)
  Strand
+
  Uniprot Entry
Q8IWZ3 
  ENSG ID
ENSG00000254996 
  Dnmivd Disease
LUSC 
    Disease Relevance (Click to Show/Hide)
         2A01: Primary neoplasms of meninges Meningioma [Primary neoplasms of meninges]
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         2B70: Malignant neoplasms of oesophagus Barrett's esophagus and esophageal adenocarcinoma [Malignant neoplasms of oesophagus]
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         2B90: Malignant neoplasms of colon Colorectal cancer [Malignant neoplasms of colon]
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         2C60: Carcinoma of breast Breast cancer [Carcinoma of breast]
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         4A40: Lupus erythematosus Systemic lupus erythematosus (SLE) [Lupus erythematosus]
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         5B81: Obesity Obesity [Obesity]
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         6E8Z: Mental, behavioural or neurodevelopmental disorders Psychiatric disorders [Mental, behavioural or neurodevelopmental disorders]
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         8A20: Alzheimer disease Alzheimer's disease [Alzheimer disease]
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         FA20: Rheumatoid arthritis Rheumatoid arthritis [Rheumatoid arthritis]
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         GA10: Endometriosis Endometriosis [Endometriosis]
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         XH1E13: Germinoma Germinoma [Germinoma]
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         XH3DV3: Adenoma Adenoma [Adenoma]
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         XH4S92: Leukaemia Leukemia [Leukaemia]
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         XH6PH6: Astrocytoma Astrocytoma [Astrocytoma]
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         XH7F82: Glioblastoma Glioblastoma [Glioblastoma]
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         XH7PW5: Lymphocytic leukaemia Pediatric acute lymphoblastic leukemia [Lymphocytic leukaemia]
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         XH8AA5: Acute myeloid leukaemia Acute myeloid leukemia (AML) [Acute myeloid leukaemia]
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         XH8P29: Medulloblastoma Medulloblastoma [Medulloblastoma]
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         XH98Z3: Schwannoma Schwannoma [Schwannoma]
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         XH9HQ1: Gastrointestinal stromal tumour Gastrointestinal stromal tumors (GIST) [Gastrointestinal stromal tumour]
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         XN487: Human immunodeficiency virus Human immunodeficiency virus (HIV) [Human immunodeficiency virus]
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Protein(s) with this epigenetic modification
  Protein Name: Rv2966c
     Detailed Information Pro Info click to show the detail information of this protein [1]
     Description
Rv2966c could hypermethylate the non-CpG dinucleotides at the host ANKHD1-EIF4EBP3 (geneBody) genetic loci during Mycobacterium tuberculosis H37Rv infection.

References
1 Genome-wide non-CpG methylation of the host genome during M. tuberculosis infection. Sci Rep. 2016 Apr 26;6:25006. doi: 10.1038/srep25006.

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