Details of Epigenetic Molecule(EM)

General Information of EM (ID: EM01068)
  Official Symbol
DESI2
  Official Full Name
desumoylating isopeptidase 2
  Synonym
C1orf121;CGI-146;DESI-2;FAM152A;FLJ21998;PNAS-4;PPPDE1
  Molecule Type
Protein coding
  Position On Chromosome
chr1(Start:244653103 - End:244709033)
  Strand
+
  Uniprot Entry
A0A024R5P9 
  ENSG ID
ENSG00000121644 
  Dnmivd Disease
LUSC 
    Disease Relevance (Click to Show/Hide)
         DD70: Crohn disease Crohn's disease [Crohn disease]
            Detailed Information Disease Link click to show the detail information of this Disease
         XH8P29: Medulloblastoma Medulloblastoma [Medulloblastoma]
            Detailed Information Disease Link click to show the detail information of this Disease
Protein(s) with this epigenetic modification
  Protein Name: Rv2966c
     Detailed Information Pro Info click to show the detail information of this protein [1]
     Description
Rv2966c could hypermethylate the non-CpG dinucleotides at the host DESI2 (geneBody) genetic loci during Mycobacterium tuberculosis H37Rv infection.
  Protein Name: Rv2966c
     Detailed Information Pro Info click to show the detail information of this protein [1]
     Description
Rv2966c could hypermethylate the non-CpG dinucleotides at the host DESI2 (intergenic) genetic loci during Mycobacterium tuberculosis H37Rv infection.
  Protein Name: Rv2966c
     Detailed Information Pro Info click to show the detail information of this protein [1]
     Description
Rv2966c could hypomethylate the non-CpG dinucleotides at the host DESI2 (intergenic) genetic loci during Mycobacterium tuberculosis H37Rv infection.

References
1 Genome-wide non-CpG methylation of the host genome during M. tuberculosis infection. Sci Rep. 2016 Apr 26;6:25006. doi: 10.1038/srep25006.

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